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Mabs|February 6, 2018
A novel bicistronic gene design couples stable cell line selection with a fucose switch in a designer CHO host to produce native and afucosylated glycoform antibodiesGargi Roy, Tom Martin, Arnita Barnes, et al.
Biotechnology Progress|April 28, 2023
CHO synthetic promoters improve expression and product quality of biotherapeutic proteinsSi Nga Sou, Claire L Harris, Rebecca Williams, et al.
Biotechnology and Bioengineering|February 1, 2023
Accelerated cell culture process development and characterization for cilgavimab/tixagevimab (AZD7442) for the prevention and treatment of COVID-19Michael W Handlogten, Stefanie Bosley, Sarah Dunn, et al.
Computational and Structural Biotechnology Journal|January 6, 2025
Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodiesYing Bai, Ivan Domenech Mercadé, Ramy Elgendy, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 7, 2025
Deciphering the determinants of recombinant protein expression across the human secretomeHelen O Masson, Pablo Di Giusto, Chih-Chung Kuo, et al.
Protein Engineering, Design & Selection : PEDS|January 29, 2017
Engineering the expression of an anti-interleukin-13 antibody through rational design and mutagenesisBojana Popovic, Suzanne Gibson, Tarik Senussi, et al.
Mabs|February 26, 2026
A cell line development vector strategy for improved expression of a trispecific T-cell engager in CHORajesh K Mistry, Chendi Nui, Giulia Lambiase, et al.
Cell Reports|June 15, 2022
Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cellsRasool Saghaleyni, Magdalena Malm, Noah Moruzzi, et al.
Journal of Biotechnology|March 2, 2020
A platform for context-specific genetic engineering of recombinant protein production by CHO cellsJoseph F Cartwright, Claire L Arnall, Yash D Patel, et al.
Metabolic Engineering|March 18, 2022
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteinsMagdalena Malm, Chih-Chung Kuo, Mona Moradi Barzadd, et al.
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