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Journal of Medicinal Chemistry|September 18, 2009
Aminoimidazoles as potent and selective human beta-secretase (BACE1) inhibitorsMichael S Malamas, Jim Erdei, Iwan Gunawan, et al.Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|November 19, 2016
Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral CortexJenny Häggkvist, Miklós Tóth, Lenke Tari, et al.European Journal of Nuclear Medicine and Molecular Imaging|August 24, 2022
Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [<sup>11</sup>C]CHDI-00485180-R and [<sup>11</sup>C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtinAline Delva, Michel Koole, Kim Serdons, et al.Journal of Medicinal Chemistry|December 9, 2009
Design and synthesis of 5,5'-disubstituted aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitorsMichael S Malamas, Jim Erdei, Iwan Gunawan, et al.Aging Cell|August 24, 2024
Age-related increase of CD38 directs osteoclastogenic potential of monocytic myeloid-derived suppressor cells through mitochondrial dysfunction in male miceRamkumar Thiyagarajan, Lixia Zhang, Omar D Glover, et al.European Journal of Nuclear Medicine and Molecular Imaging|June 17, 2025
PET imaging with [¹¹C]CHDI-00485180-R, designed as radioligand for aggregated mutant huntingtin, in people with Huntington's diseaseAline Delva, Michel Koole, Kim Serdons, et al.Bioorganic & Medicinal Chemistry|January 5, 2010
Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitorsMichael S Malamas, Keith Barnes, Matthew Johnson, et al.Bioorganic & Medicinal Chemistry Letters|August 13, 2011
New pyrazolyl and thienyl aminohydantoins as potent BACE1 inhibitors: exploring the S2' regionMichael S Malamas, Jim Erdei, Iwan Gunawan, et al.Bioorganic & Medicinal Chemistry Letters|March 6, 2010
Pyridinyl aminohydantoins as small molecule BACE1 inhibitorsPing Zhou, Yanfang Li, Yi Fan, et al.Cells|October 15, 2025
Multimodal Exploration Offers Novel Insights into the Transcriptomic and Epigenomic Landscape of the Human Submandibular GlandsErich Horeth, Theresa Wrynn, Jason M Osinski, et al.Pageof 8