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Molecular Cancer Therapeutics|December 19, 2014
Sunitinib dose escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modificationsRemi Adelaiye, Eric Ciamporcero, Kiersten Marie Miles, et al.Bioorganic & Medicinal Chemistry Letters|March 13, 2010
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitorsMichael S Malamas, Keith Barnes, Yu Hui, et al.Nature Biotechnology|November 9, 2007
The OBO Foundry: coordinated evolution of ontologies to support biomedical data integrationBarry Smith, Michael Ashburner, Cornelius Rosse, et al.Plos One|March 27, 2019
Meso scale discovery-based assays for the detection of aggregated huntingtinWolfgang Reindl, Barbara Baldo, Jana Schulz, et al.Peptides|April 1, 2006
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesisKristie Grove Bridges, Rajiv Chopra, Laura Lin, et al.Bioorganic & Medicinal Chemistry Letters|December 11, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocketLee D Jennings, Derek C Cole, Joseph R Stock, et al.Bioorganic & Medicinal Chemistry Letters|December 29, 2007
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pocketsDerek C Cole, Joseph R Stock, Rajiv Chopra, et al.Bioorganic & Medicinal Chemistry Letters|December 5, 2009
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitorsPawel Nowak, Derek C Cole, Ann Aulabaugh, et al.Science Translational Medicine|February 2, 2022
Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's diseaseDaniele Bertoglio, Jonathan Bard, Manuela Hessmann, et al.Proceedings of the National Academy of Sciences of the United States of America|June 19, 2008
Enhanced clearance of Abeta in brain by sustaining the plasmin proteolysis cascadeJ Steven Jacobsen, Thomas A Comery, Robert L Martone, et al.Pageof 8