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Journal of Peptide Science : an Official Publication of the European Peptide Society|November 24, 2006
Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptidesPrashant R Agrawal, Mathias W Hofmann, Nico J Meeuwenoord, et al.Iscience|December 9, 2020
Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane HelixCharlotte Spitz, Christine Schlosser, Nadja Guschtschin-Schmidt, et al.Journal of the American Chemical Society|December 26, 2012
The backbone dynamics of the amyloid precursor protein transmembrane helix provides a rationale for the sequential cleavage mechanism of γ-secretaseOxana Pester, Paul J Barrett, Daniel Hornburg, et al.Nature Communications|July 2, 2025
Charting γ-secretase substrates by explainable AIStephan Breimann, Frits Kamp, Gabriele Basset, et al.Proceedings of the National Academy of Sciences of the United States of America|August 4, 2010
Amyloid beta 42 peptide (Abeta42)-lowering compounds directly bind to Abeta and interfere with amyloid precursor protein (APP) transmembrane dimerizationLuise Richter, Lisa-Marie Munter, Julia Ness, et al.Scientific Reports|December 5, 2022
Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavageAlkmini A Papadopoulou, Walter Stelzer, Mara Silber, et al.Biophysical Journal|May 28, 2019
Modulating Hinge Flexibility in the APP Transmembrane Domain Alters γ-Secretase CleavageAlexander Götz, Nadine Mylonas, Philipp Högel, et al.EMBO Molecular Medicine|September 7, 2022
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ-secretase activityGökhan Güner, Marlene Aßfalg, Kai Zhao, et al.Pageof 7