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Recent Patents on Cardiovascular Drug Discovery
|
September 30, 2010
Challenges and promises of developing thrombin receptor antagonists
Jing Yang, Ke Xu, Dietmar Seiffert
Drug Discovery Today
|
May 6, 2014
Inhibition of Factor XI activity as a promising antithrombotic strategy
Zhu Chen, Dietmar Seiffert, Brian Hawes
Proceedings of the National Academy of Sciences of the United States of America
|
July 27, 2007
Feedback activation of factor XI by thrombin does not occur in plasma
Donna L Pedicord, Dietmar Seiffert, Yuval Blat
Biochemistry
|
September 15, 2004
Substrate-dependent modulation of the mechanism of factor XIa inhibition
Donna L Pedicord, Dietmar Seiffert, Yuval Blat
Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|
March 30, 2005
Using thrombelastography to determine the efficacy of the platelet glycoprotein IIb/IIIa antagonist, roxifiban, on platelet/fibrin-mediated clot dynamics in humans
Shaker A Mousa, Jeffrey M Bozarth, Dietmar Seiffert, et al.
Journal of Pharmaceutical and Biomedical Analysis
|
May 9, 2007
Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist
Yu Chen Barrett, William Ebling, Henry Pieniaszek, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 8, 2016
Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
Xueping Zhou, Weizhen Wu, Lin Chu, et al.
Thrombosis Research
|
February 5, 2003
Effects of glycoprotein IIb/IIIa antagonists on platelet activation: development of a transfer method to mimic peak to trough receptor occupancy
Jeffrey T Billheimer, Bokang He, Susan M Spitz, et al.
Clinical and Translational Science
|
September 24, 2021
First-in-human study of milvexian, an oral, direct, small molecule factor XIa inhibitor
Vidya Perera, Zhaoqing Wang, Joseph Luettgen, et al.
Platelets
|
July 3, 2023
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants
Samira Merali, Zhaoqing Wang, Charles Frost, et al.
Page
of 5
Search research articles
Search
Showing results (1-10 of 50) with videos related to
Sort By:
Page
of 5
Recent Patents on Cardiovascular Drug Discovery
|
September 30, 2010
Challenges and promises of developing thrombin receptor antagonists
Jing Yang, Ke Xu, Dietmar Seiffert
Drug Discovery Today
|
May 6, 2014
Inhibition of Factor XI activity as a promising antithrombotic strategy
Zhu Chen, Dietmar Seiffert, Brian Hawes
Proceedings of the National Academy of Sciences of the United States of America
|
July 27, 2007
Feedback activation of factor XI by thrombin does not occur in plasma
Donna L Pedicord, Dietmar Seiffert, Yuval Blat
Biochemistry
|
September 15, 2004
Substrate-dependent modulation of the mechanism of factor XIa inhibition
Donna L Pedicord, Dietmar Seiffert, Yuval Blat
Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|
March 30, 2005
Using thrombelastography to determine the efficacy of the platelet glycoprotein IIb/IIIa antagonist, roxifiban, on platelet/fibrin-mediated clot dynamics in humans
Shaker A Mousa, Jeffrey M Bozarth, Dietmar Seiffert, et al.
Journal of Pharmaceutical and Biomedical Analysis
|
May 9, 2007
Validation and implementation of drug-dependent antibody assays in clinical trials for safety monitoring of patients dosed with roxifiban, an orally bioavailable glycoprotein IIb/IIIa antagonist
Yu Chen Barrett, William Ebling, Henry Pieniaszek, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
July 8, 2016
Apixaban Inhibits Cerebral Microembolic Signals Derived from Carotid Arterial Thrombosis in Rabbits
Xueping Zhou, Weizhen Wu, Lin Chu, et al.
Thrombosis Research
|
February 5, 2003
Effects of glycoprotein IIb/IIIa antagonists on platelet activation: development of a transfer method to mimic peak to trough receptor occupancy
Jeffrey T Billheimer, Bokang He, Susan M Spitz, et al.
Clinical and Translational Science
|
September 24, 2021
First-in-human study of milvexian, an oral, direct, small molecule factor XIa inhibitor
Vidya Perera, Zhaoqing Wang, Joseph Luettgen, et al.
Platelets
|
July 3, 2023
First-in-human study to assess the safety, pharmacokinetics, and pharmacodynamics of BMS-986141, a novel, reversible, small-molecule, PAR4 agonist in non-Japanese and Japanese healthy participants
Samira Merali, Zhaoqing Wang, Charles Frost, et al.
Page
of 5