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JCI Insight
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December 22, 2021
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep
Chantal M Ferguson, Bruno Mdc Godinho, Julia F Alterman, et al.
ACS Pharmacology & Translational Science
|
June 19, 2025
A Therapeutic Small-Interfering RNA Potentiates Janus Kinase 1 Modulation for the Treatment of Dog Inflammatory Diseases
Qi Tang, Hassan H Fakih, Katherine Y Gross, et al.
Molecular Therapy. Nucleic Acids
|
March 20, 2026
An siRNA targeting <i>S6k1</i> identifies photoreceptor phospholipid metabolism as a contributor to lipid buildup in age-related macular degeneration
Shun-Yun Cheng, Delaney Giguere, San Kim, et al.
Nucleic Acids Research
|
February 13, 2018
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo
Matthew R Hassler, Anton A Turanov, Julia F Alterman, et al.
Science Translational Medicine
|
March 18, 2026
Lowering the <i>HTT1a</i> transcript as an effective therapy for Huntington's disease in a knockin mouse model
Aikaterini Smaragdi Papadopoulou, Julia Alterman, Christian Landles, et al.
Nature Biotechnology
|
November 20, 2018
RNAi modulation of placental sFLT1 for the treatment of preeclampsia
Anton A Turanov, Agnes Lo, Matthew R Hassler, et al.
Nucleic Acids Research
|
December 23, 2025
Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs
Hassan H Fakih, Clemens Lochmann, Rosemary Gagnon, et al.
Biorxiv : the Preprint Server for Biology
|
June 9, 2023
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy
Ken Yamada, Vignesh Narayan Hariharan, Jillian Caiazzi, et al.
Nucleic Acids Research
|
August 3, 2022
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts
Minwook Shin, Io Long Chan, Yuming Cao, et al.
Biorxiv : the Preprint Server for Biology
|
July 9, 2024
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice
Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores, et al.
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Search research articles
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Showing results (61-70 of 81) with videos related to
Sort By:
Page
of 9
JCI Insight
|
December 22, 2021
Comparative route of administration studies using therapeutic siRNAs show widespread gene modulation in Dorset sheep
Chantal M Ferguson, Bruno Mdc Godinho, Julia F Alterman, et al.
ACS Pharmacology & Translational Science
|
June 19, 2025
A Therapeutic Small-Interfering RNA Potentiates Janus Kinase 1 Modulation for the Treatment of Dog Inflammatory Diseases
Qi Tang, Hassan H Fakih, Katherine Y Gross, et al.
Molecular Therapy. Nucleic Acids
|
March 20, 2026
An siRNA targeting <i>S6k1</i> identifies photoreceptor phospholipid metabolism as a contributor to lipid buildup in age-related macular degeneration
Shun-Yun Cheng, Delaney Giguere, San Kim, et al.
Nucleic Acids Research
|
February 13, 2018
Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo
Matthew R Hassler, Anton A Turanov, Julia F Alterman, et al.
Science Translational Medicine
|
March 18, 2026
Lowering the <i>HTT1a</i> transcript as an effective therapy for Huntington's disease in a knockin mouse model
Aikaterini Smaragdi Papadopoulou, Julia Alterman, Christian Landles, et al.
Nature Biotechnology
|
November 20, 2018
RNAi modulation of placental sFLT1 for the treatment of preeclampsia
Anton A Turanov, Agnes Lo, Matthew R Hassler, et al.
Nucleic Acids Research
|
December 23, 2025
Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs
Hassan H Fakih, Clemens Lochmann, Rosemary Gagnon, et al.
Biorxiv : the Preprint Server for Biology
|
June 9, 2023
Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy
Ken Yamada, Vignesh Narayan Hariharan, Jillian Caiazzi, et al.
Nucleic Acids Research
|
August 3, 2022
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts
Minwook Shin, Io Long Chan, Yuming Cao, et al.
Biorxiv : the Preprint Server for Biology
|
July 9, 2024
RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice
Alexandra Weiss, James W Gilbert, Iris Valeria Rivera Flores, et al.
Page
of 9