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Journal of Medicinal Chemistry|January 29, 2019
Synthesis and Structural/Functional Characterization of Selective M14 Metallocarboxypeptidase Inhibitors Based on Phosphinic Pseudopeptide Scaffold: Implications on the Design of Specific Optical ProbesGiovanni Covaleda, Pablo Gallego, Josep Vendrell, et al.Scientific Reports|August 14, 2021
The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class IGeorge Mavridis, Anastasia Mpakali, Jerome Zoidakis, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|February 3, 2015
Probing the mechanism of allylic substitution of Morita-Baylis-Hillman acetates (MBHAs) by using the silyl phosphonite paradigm: scope and applications of a versatile transformationMaria Kalyva, Alexandros L Zografos, Era Kapourani, et al.Proceedings of the National Academy of Sciences of the United States of America|December 18, 2019
Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1Petros Giastas, Anastasia Mpakali, Athanasios Papakyriakou, et al.Annals of the Rheumatic Diseases|July 2, 2015
Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitisLiye Chen, Anna Ridley, Ariane Hammitzsch, et al.The Journal of Biological Chemistry|September 10, 2010
The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407Colin S Anthony, Hazel R Corradi, Sylva L U Schwager, et al.Cancer Immunology, Immunotherapy : CII|June 22, 2019
Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)Despoina Koumantou, Eilon Barnea, Adrian Martin-Esteban, et al.The Journal of Biological Chemistry|March 19, 2020
A systematic re-examination of processing of MHCI-bound antigenic peptide precursors by endoplasmic reticulum aminopeptidase 1George Mavridis, Richa Arya, Alexander Domnick, et al.Proceedings of the National Academy of Sciences of the United States of America|November 20, 2013
Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responsesEfthalia Zervoudi, Emmanuel Saridakis, James R Birtley, et al.Journal of Medicinal Chemistry|September 9, 2016
Optimization and Structure-Activity Relationships of Phosphinic Pseudotripeptide Inhibitors of Aminopeptidases That Generate Antigenic PeptidesParaskevi Kokkala, Anastasia Mpakali, Francois-Xavier Mauvais, et al.Pageof 6