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Biorxiv : the Preprint Server for Biology
|
August 6, 2025
Machine Learning Resolves Functional Phenotypes and Therapeutic Responses in KCNQ2 Developmental Epileptic Encephalopathy iPSC Models
Dina Simkin, Syed M A Wafa, Mennat Gharib, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
September 25, 2015
Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression
Dina Simkin, Shoai Hattori, Natividad Ybarra, et al.
Trends in Pharmacological Sciences
|
April 15, 2022
'Channeling' therapeutic discovery for epileptic encephalopathy through iPSC technologies
Dina Simkin, Christina Ambrosi, Kelly A Marshall, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|
February 19, 2019
Peptide-siRNA Supramolecular Particles for Neural Cell Transfection
Armando Hernandez-Garcia, Zaida Álvarez, Dina Simkin, et al.
ACS Biomaterials Science & Engineering
|
March 18, 2026
Design of Neuronal Supramolecular Scaffolds Integrating Cell Signaling and Electrical Conductivity
Anna Metlushko, Nicholas A Sather, Timmy Fyrner, et al.
Stem Cell Reports
|
March 11, 2022
Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls
Dina Simkin, Vasileios Papakis, Bernabe I Bustos, et al.
Elife
|
February 5, 2021
Dyshomeostatic modulation of Ca<sup>2+</sup>-activated K<sup>+</sup> channels in a human neuronal model of KCNQ2 encephalopathy
Dina Simkin, Kelly A Marshall, Carlos G Vanoye, et al.
Nature Communications
|
February 22, 2023
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, et al.
Biological Psychiatry
|
December 29, 2022
Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons
Euan Parnell, Lorenza Culotta, Marc P Forrest, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 17, 2021
Cognitive aging is associated with redistribution of synaptic weights in the hippocampus
Eric W Buss, Nicola J Corbett, Joshua G Roberts, et al.
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Showing results (11-20 of 21) with videos related to
Sort By:
Page
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Biorxiv : the Preprint Server for Biology
|
August 6, 2025
Machine Learning Resolves Functional Phenotypes and Therapeutic Responses in KCNQ2 Developmental Epileptic Encephalopathy iPSC Models
Dina Simkin, Syed M A Wafa, Mennat Gharib, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|
September 25, 2015
Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression
Dina Simkin, Shoai Hattori, Natividad Ybarra, et al.
Trends in Pharmacological Sciences
|
April 15, 2022
'Channeling' therapeutic discovery for epileptic encephalopathy through iPSC technologies
Dina Simkin, Christina Ambrosi, Kelly A Marshall, et al.
Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|
February 19, 2019
Peptide-siRNA Supramolecular Particles for Neural Cell Transfection
Armando Hernandez-Garcia, Zaida Álvarez, Dina Simkin, et al.
ACS Biomaterials Science & Engineering
|
March 18, 2026
Design of Neuronal Supramolecular Scaffolds Integrating Cell Signaling and Electrical Conductivity
Anna Metlushko, Nicholas A Sather, Timmy Fyrner, et al.
Stem Cell Reports
|
March 11, 2022
Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls
Dina Simkin, Vasileios Papakis, Bernabe I Bustos, et al.
Elife
|
February 5, 2021
Dyshomeostatic modulation of Ca<sup>2+</sup>-activated K<sup>+</sup> channels in a human neuronal model of KCNQ2 encephalopathy
Dina Simkin, Kelly A Marshall, Carlos G Vanoye, et al.
Nature Communications
|
February 22, 2023
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P Forrest, Marc Dos Santos, Nicolas H Piguel, et al.
Biological Psychiatry
|
December 29, 2022
Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons
Euan Parnell, Lorenza Culotta, Marc P Forrest, et al.
Proceedings of the National Academy of Sciences of the United States of America
|
February 17, 2021
Cognitive aging is associated with redistribution of synaptic weights in the hippocampus
Eric W Buss, Nicola J Corbett, Joshua G Roberts, et al.
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of 3