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Expert Opinion on Drug Metabolism & Toxicology|August 2, 2012
Strategies for the generation, validation and application of in silico ADMET models in lead generation and optimizationMatthew Paul Gleeson, Dino Montanari
Molecular Informatics|August 3, 2019
Investigation of Factors Affecting the Performance of in silico Volume Distribution QSAR Models for Human, Rat, Mouse, Dog & MonkeySaw Simeon, Dino Montanari, Matthew Paul Gleeson
Expert Opinion on Drug Discovery|July 25, 2012
Drug efficiency: a new concept to guide lead optimization programs towards the selection of better clinical candidatesSimone Braggio, Dino Montanari, Tino Rossi, et al.
Journal of Pharmaceutical Sciences|August 30, 2012
In vitro measurement of drug efficiency index to aid early lead optimizationKlara Valko, Elisabetta Chiarparin, Shenaz Nunhuck, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|December 1, 2009
Development and validation of a high-throughput method for the quantitative analysis of D-amphetamine in rat blood using liquid chromatography/MS3 on a hybrid triple quadrupole-linear ion trap mass spectrometer and its application to a pharmacokinetic studyNicola Cesari, Stefano Fontana, Dino Montanari, et al.
Nature Reviews. Drug Discovery|March 2, 2011
Probing the links between in vitro potency, ADMET and physicochemical parametersM Paul Gleeson, Anne Hersey, Dino Montanari, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|September 4, 2014
Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich cultureLassina Badolo, Bente Jensen, Carolina Säll, et al.
Drug Metabolism Letters|January 5, 2011
A comparative study of the CYP450 inhibition potential of marketed drugs using two fluorescence based assay platforms routinely used in the pharmaceutical industryMahmud Kajbaf, Raffaele Longhi, Dino Montanari, et al.
Expert Opinion on Drug Discovery|June 1, 2012
Application of drug efficiency index in drug discovery: a strategy towards low therapeutic doseDino Montanari, Elisabetta Chiarparin, Matthew Paul Gleeson, et al.
European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V|November 10, 2021
Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from miceBurak Ozgür, Lasse Saaby, Christian Janfelt, et al.
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