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Bioorganic & Medicinal Chemistry Letters|August 2, 2005
Cyclic sulfamide gamma-secretase inhibitorsTim Sparey, Dirk Beher, Jonathan Best, et al.
Neurobiology of Aging|August 18, 2004
Novel aspects of accumulation dynamics and A beta composition in transgenic models of ADHuw D Lewis, Dirk Beher, David Smith, et al.
Bioorganic & Medicinal Chemistry Letters|December 18, 2004
A novel series of potent gamma-secretase inhibitors based on a benzobicyclo[4.2.1]nonane coreStephen J Lewis, Adrian L Smith, Joseph G Neduvelil, et al.
Chemistry & Biology|February 24, 2007
Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signalingHuw D Lewis, Matthew Leveridge, Peter R Strack, et al.
Acta Neuropathologica|November 15, 2018
The metalloprotease ADAMTS4 generates N-truncated Aβ4-x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer's diseaseSusanne Walter, Thorsten Jumpertz, Melanie Hüttenrauch, et al.
Bioorganic & Medicinal Chemistry Letters|November 9, 2005
4-substituted cyclohexyl sulfones as potent, orally active gamma-secretase inhibitorsIan Churcher, Dirk Beher, Jonathan D Best, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 14, 2006
LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's diseaseJohn Majercak, William J Ray, Amy Espeseth, et al.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|September 28, 2021
Current directions in tau research: Highlights from Tau 2020Claire Sexton, Heather Snyder, Dirk Beher, et al.
Alzheimer'S & Dementia : the Journal of the Alzheimer'S Association|September 24, 2024
A framework for translating tauopathy therapeutics: Drug discovery to clinical trialsHoward H Feldman, Jeffrey L Cummings, Adam L Boxer, et al.
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