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Organic & Biomolecular Chemistry|January 20, 2018
Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel"Zhongxia Zhou, Tao Liu, Dongwei Kang, et al.
European Journal of Medicinal Chemistry|March 21, 2016
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocketQing Meng, Xuwang Chen, Dongwei Kang, et al.
Bioorganic & Medicinal Chemistry Letters|March 15, 2018
First discovery of a potential carbonate prodrug of NNRTI drug candidate RDEA427 with submicromolar inhibitory activity against HIV-1 K103N/Y181C double mutant strainBoshi Huang, Xinhao Liu, Ye Tian, et al.
Molecules (Basel, Switzerland)|November 27, 2019
Design and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2<i>H</i>-Benzo[<i>g</i>]indazole Derivatives: Antiproliferative and Antibacterial ActivityViviana Cuartas, María Del Pilar Crespo, Eva-María Priego, et al.
Current Pharmaceutical Design|November 24, 2016
Structural Modifications of Diarylpyrimidine-quinolone Hybrids as Potent HIV-1 NNRTIs with an Improved Drug Resistance ProfileTian-Qi Mao, Qiu-Qin He, Wen-Xue Chen, et al.
Bioorganic & Medicinal Chemistry|August 16, 2014
Exploiting the anti-HIV 6-desfluoroquinolones to design multiple ligandsLuca Sancineto, Nunzio Iraci, Maria Letizia Barreca, et al.
Communications Biology|November 23, 2024
Ibetazol, a novel inhibitor of importin β1-mediated nuclear importThomas Vercruysse, Els Vanstreels, Maarten Jacquemyn, et al.
Bioorganic & Medicinal Chemistry|September 24, 2013
Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studiesHai-Qiu Wu, Zi-Hong Yan, Wen-Xue Chen, et al.
Journal of Virology|June 29, 2012
Intracytoplasmic trapping of influenza virus by a lipophilic derivative of aglycoristocetinEvelien Vanderlinden, Els Vanstreels, Eline Boons, et al.
Scientific Reports|March 23, 2018
Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale ThermophoresisTanja Bartoschik, Stefanie Galinec, Christian Kleusch, et al.
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