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American Journal of Human Genetics|November 8, 2018
Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis SimplexMaria-Teresa Romano, Aylar Tafazzoli, Maximilian Mattern, et al.
Cell Host & Microbe|December 20, 2014
Nef proteins of epidemic HIV-1 group O strains antagonize human tetherinSilvia F Kluge, Katharina Mack, Shilpa S Iyer, et al.
Bioorganic & Medicinal Chemistry Letters|February 28, 2024
The discovery of novel and potent indazole NLRP3 inhibitors enabled by DNA-encoded library screeningGeorge Hartman, Paul Humphries, Robert Hughes, et al.
Nature Communications|April 28, 2022
Deficiency in coatomer complex I causes aberrant activation of STING signallingAnnemarie Steiner, Katja Hrovat-Schaale, Ignazia Prigione, et al.
The Journal of Biological Chemistry|January 22, 2019
Species-specific differences in nonlysosomal glucosylceramidase GBA2 function underlie locomotor dysfunction arising from loss-of-function mutationsMarina A Woeste, Sina Stern, Diana N Raju, et al.
Nature Communications|April 17, 2019
CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylationMalgorzata Krajewska, Ruben Dries, Andrew V Grassetti, et al.
Nature Chemical Biology|August 30, 2016
Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitorsTinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, et al.
The Journal of Experimental Medicine|October 31, 2022
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infectionLea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, et al.
Molecular Cell|April 1, 2019
MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription ElongationApoorva Baluapuri, Julia Hofstetter, Nevenka Dudvarski Stankovic, et al.
The Journal of Allergy and Clinical Immunology|December 30, 2020
NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severityJonas Moecking, Pawat Laohamonthonkul, Katelyn Chalker, et al.
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