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ACS Pharmacology & Translational Science|March 15, 2022
Identification of Inhibitors of SARS-CoV-2 3CL-Pro Enzymatic Activity Using a Small Molecule in Vitro Repurposing ScreenMaria Kuzikov, Elisa Costanzi, Jeanette Reinshagen, et al.Neuron|November 29, 2022
Anatomical barriers against SARS-CoV-2 neuroinvasion at vulnerable interfaces visualized in deceased COVID-19 patientsMona Khan, Marnick Clijsters, Sumin Choi, et al.Microorganisms|August 26, 2022
Need for a Standardized Translational Drug Development Platform: Lessons Learned from the Repurposing of Drugs for COVID-19Frauke Assmus, Jean-Sélim Driouich, Rana Abdelnabi, et al.Biorxiv : the Preprint Server for Biology|July 16, 2025
Open-science discovery of DNDI-6510, a compound that addresses genotoxic and metabolic liabilities of the COVID Moonshot SARS-CoV-2 Mpro lead inhibitorEd J Griffen, Daren Fearon, Briana L McGovern, et al.Biorxiv : the Preprint Server for Biology|July 16, 2025
Discovery of orally bioavailable Zika and West Nile Virus antiviral compounds targeting the NS2B-NS3 proteaseNathaniel T Kenton, Haim Barr, Artem Cherepakha, et al.Biorxiv : the Preprint Server for Biology|June 23, 2021
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effectsSirle Saul, Marwah Karim, Luca Ghita, et al.The Journal of Clinical Investigation|August 15, 2023
Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effectsSirle Saul, Marwah Karim, Luca Ghita, et al.Ebiomedicine|March 22, 2021
Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trialLaurens Liesenborghs, Isabel Spriet, Dirk Jochmans, et al.Journal of Medicinal Chemistry|June 30, 2025
Discovery and Preclinical Profile of ALG-097558, a Pan-Coronavirus 3CLpro InhibitorDorothée Bardiot, David C McGowan, Kusum Gupta, et al.Nature Communications|November 18, 2020
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamstersRobbert Boudewijns, Hendrik Jan Thibaut, Suzanne J F Kaptein, et al.Pageof 12