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Dirk Kessler

Showing results (11-20 of 28) with videos related to

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Chemistry (Weinheim an Der Bergstrasse, Germany)|June 25, 2019
KRAS Binders Hidden in NatureAndreas Bergner, Xiaoling Cockcroft, Gerhard Fischer, et al.
Angewandte Chemie (International Ed. in English)|May 19, 2020
PI by NMR: Probing CH-π Interactions in Protein-Ligand Complexes by NMR SpectroscopyGerald Platzer, Moriz Mayer, Andreas Beier, et al.
Molecular Cancer Therapeutics|October 7, 2015
BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose HomeostasisMichael P Sanderson, Joshua Apgar, Pilar Garin-Chesa, et al.
Communications Biology|July 24, 2024
A ligand discovery toolbox for the WWE domain family of human E3 ligasesLena Münzker, Serah W Kimani, Milan M Fowkes, et al.
Journal of Medicinal Chemistry|July 15, 2024
Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical AssaysThomas Gerstberger, Helmut Berger, Frank H Büttner, et al.
Journal of Medicinal Chemistry|January 17, 2025
Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2)Krzysztof M Zak, Alex G Waterson, Leonhard Geist, et al.
Journal of Medicinal Chemistry|October 25, 2016
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 InteractionAndreas Gollner, Dorothea Rudolph, Heribert Arnhof, et al.
Nature Chemical Biology|July 23, 2021
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domainDaniel B Grabarczyk, Olga A Petrova, Luiza Deszcz, et al.
Cell Chemical Biology|February 12, 2026
Systematic cysteine scanning identifies a druggable pocket in oncogenic KRASLaurens M van Tienen, Shadwa Bayoumi, Khaja Muneeruddin, et al.
Chemmedchem|December 4, 2020
Getting a Grip on the Undrugged: Targeting β-Catenin with Fragment-Based MethodsDirk Kessler, Moriz Mayer, Stephan K Zahn, et al.
Pageof 3

Showing results (11-20 of 28) with videos related to

Sort By:
Pageof 3
Chemistry (Weinheim an Der Bergstrasse, Germany)|June 25, 2019
KRAS Binders Hidden in NatureAndreas Bergner, Xiaoling Cockcroft, Gerhard Fischer, et al.
Angewandte Chemie (International Ed. in English)|May 19, 2020
PI by NMR: Probing CH-π Interactions in Protein-Ligand Complexes by NMR SpectroscopyGerald Platzer, Moriz Mayer, Andreas Beier, et al.
Molecular Cancer Therapeutics|October 7, 2015
BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose HomeostasisMichael P Sanderson, Joshua Apgar, Pilar Garin-Chesa, et al.
Communications Biology|July 24, 2024
A ligand discovery toolbox for the WWE domain family of human E3 ligasesLena Münzker, Serah W Kimani, Milan M Fowkes, et al.
Journal of Medicinal Chemistry|July 15, 2024
Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical AssaysThomas Gerstberger, Helmut Berger, Frank H Büttner, et al.
Journal of Medicinal Chemistry|January 17, 2025
Discovery of Small Molecules that Bind to Son of Sevenless 2 (SOS2)Krzysztof M Zak, Alex G Waterson, Leonhard Geist, et al.
Journal of Medicinal Chemistry|October 25, 2016
Discovery of Novel Spiro[3H-indole-3,2'-pyrrolidin]-2(1H)-one Compounds as Chemically Stable and Orally Active Inhibitors of the MDM2-p53 InteractionAndreas Gollner, Dorothea Rudolph, Heribert Arnhof, et al.
Nature Chemical Biology|July 23, 2021
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domainDaniel B Grabarczyk, Olga A Petrova, Luiza Deszcz, et al.
Cell Chemical Biology|February 12, 2026
Systematic cysteine scanning identifies a druggable pocket in oncogenic KRASLaurens M van Tienen, Shadwa Bayoumi, Khaja Muneeruddin, et al.
Chemmedchem|December 4, 2020
Getting a Grip on the Undrugged: Targeting β-Catenin with Fragment-Based MethodsDirk Kessler, Moriz Mayer, Stephan K Zahn, et al.
Pageof 3