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Proceedings of the National Academy of Sciences of the United States of America|November 6, 2013
A genetic strategy to identify targets for the development of drugs that prevent bacterial persistenceJee-Hyun Kim, Kathryn M O'Brien, Ritu Sharma, et al.Journal of Medicinal Chemistry|April 22, 2026
Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosisQiang Liu, Curtis A Engelhart, Joshua B Wallach, et al.Nature Communications|April 23, 2022
CinA mediates multidrug tolerance in Mycobacterium tuberculosisKaj M Kreutzfeldt, Robert S Jansen, Travis E Hartman, et al.Cell Systems|July 30, 2025
Integration of multi-modal measurements identifies critical mechanisms of tuberculosis drug actionWilliam C Johnson, Ares Alivisatos, Trever C Smith, et al.Chemical Science|May 2, 2025
Tailored phenyl ureas eradicate drug-resistant Mycobacterium tuberculosis by targeting mycolic acid cell wall assemblyDietrich Mostert, Josef Braun, Matthew D Zimmerman, et al.Nature Microbiology|January 10, 2025
A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicityAlexander A Smith, Hongwei Su, Joshua Wallach, et al.Biorxiv : the Preprint Server for Biology|December 4, 2023
A "suicide" BCG strain provides enhanced immunogenicity and robust protection against Mycobacterium tuberculosis in macaquesAlexander A Smith, Hongwei Su, Joshua Wallach, et al.Science Advances|April 1, 2026
A periplasmic protein complex mediates arabinofuranosyltransferase activity and intrinsic drug resistance in Mycobacterium tuberculosisThaís Klevorn, Christopher Brown, Christine D Hardy, et al.Journal of Medicinal Chemistry|May 2, 2022
Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis ActivityPreshendren Govender, Rudolf Müller, Kawaljit Singh, et al.Nature Microbiology|May 31, 2022
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosisShuqi Li, Nicholas C Poulton, Jesseon S Chang, et al.Pageof 14