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Nature Communications|November 3, 2025
Reference-based chemical-genetic interaction profiling to elucidate small molecule mechanism of action in Mycobacterium tuberculosisAustin N Bond, Marek Orzechowski, Shuting Zhang, et al.Biorxiv : the Preprint Server for Biology|February 26, 2026
Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against Mycobacterium tuberculosisClaire Naylor, Gareth A Prosser, Tracy Bayliss, et al.Biorxiv : the Preprint Server for Biology|November 28, 2023
Development of an Engineered Mycobacterium tuberculosis Strain for a Safe and Effective Tuberculosis Human Challenge ModelXin Wang, Hongwei Su, Joshua B Wallach, et al.EMBO Molecular Medicine|April 7, 2026
Integrating chemical, genetic, and feasibility assessments for anti-tubercular target validationDirk Schnappinger, Steven J Berthel, Helena I M Boshoff, et al.EMBO Molecular Medicine|December 7, 2020
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosisBei Shi Lee, Kiel Hards, Curtis A Engelhart, et al.Proceedings of the National Academy of Sciences of the United States of America|April 5, 2022
Chemical-genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacyEun-Ik Koh, Peter O Oluoch, Nadine Ruecker, et al.Journal of Medicinal Chemistry|November 10, 2023
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular ActivitySimon R Green, Caroline Wilson, Thomas C Eadsforth, et al.Science (New York, N.Y.)|February 2, 2019
Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibitionElaine Ballinger, John Mosior, Travis Hartman, et al.Nature Microbiology|January 10, 2025
Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal modelsXin Wang, Hongwei Su, Joshua B Wallach, et al.Molecular Cell|February 23, 2019
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell DeathDiana Mendes Freire, Claude Gutierrez, Acely Garza-Garcia, et al.Pageof 14