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Mbio|April 20, 2026
Utilization of a CRISPRi-based ex vivo challenge model to reveal temporally dependent gene essentiality in intracellular Mycobacterium tuberculosisMonique E Theriault, Andrew I Wong, Michael A DeJesus, et al.Nature Microbiology|February 7, 2017
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platformJeremy M Rock, Forrest F Hopkins, Alejandro Chavez, et al.Mbio|January 19, 2017
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon MutagenesisMichael A DeJesus, Elias R Gerrick, Weizhen Xu, et al.Chemistry & Biology|January 6, 2015
Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosisSae Woong Park, Dominick E Casalena, Daniel J Wilson, et al.Antimicrobial Agents and Chemotherapy|August 19, 2025
Microbiological evidence for the trisubstituted benzimidazoles targeting MmpL3 in Mycobacterium tuberculosisMengyun Zhang, Renee Allen, Lauren Ames, et al.Journal of Medicinal Chemistry|November 24, 2025
Design, Synthesis, and Biological Evaluation of Mono- and Diamino-Substituted Squaramide Derivatives as Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) SynthasePaul R Palme, Shipra Grover, Rana Abdelaziz, et al.Molecular Microbiology|June 17, 2025
The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB): A Large-Scale Guide to Genetic Conditional EssentialityAdrian Jinich, Anisha Zaveri, Michael A DeJesus, et al.The Lancet. Microbe|January 26, 2026
Controlled human infection with Mycobacterium tuberculosis: practical considerations for clinical trialsChetan Seshadri, JoAnne L Flynn, Pauline Maiello, et al.Cell|July 23, 2021
Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosisBarbara Bosch, Michael A DeJesus, Nicholas C Poulton, et al.Nature Communications|March 22, 2026
Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosisDebbie M Hunt, João Pedro Pisco, Angela Rodgers, et al.Pageof 14