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Journal of Medicinal Chemistry|November 8, 2013
Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitorsWeihe Zhang, Dehui Zhang, Michael A Stashko, et al.ACS Medicinal Chemistry Letters|June 5, 2012
Discovery of Novel Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic LeukemiaJing Liu, Chao Yang, Catherine Simpson, et al.Nature Chemical Biology|February 16, 2023
Structural basis of paralog-specific KDM2A/B nucleosome recognitionCathy J Spangler, Aleksandra Skrajna, Caroline A Foley, et al.Chemical Science|January 29, 2025
Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1Akhila Mettu, Marta Glavatskikh, Xiaowen Wang, et al.SLAS Discovery : Advancing Life Sciences R & D|May 10, 2018
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell GrowthLinas J Krulikas, Ian M McDonald, Benjamin Lee, et al.Journal of the American Chemical Society|September 10, 2019
Data-Driven Construction of Antitumor Agents with Controlled PolypharmacologyChenxiao Da, Dehui Zhang, Michael Stashko, et al.Journal of Medicinal Chemistry|November 14, 2013
Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosisWeihe Zhang, Andrew L McIver, Michael A Stashko, et al.Molecular Cancer Therapeutics|September 3, 2013
UNC569, a novel small-molecule mer inhibitor with efficacy against acute lymphoblastic leukemia in vitro and in vivoSandra Christoph, Deborah Deryckere, Jennifer Schlegel, et al.Nature Chemical Biology|November 16, 2021
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localizationDavid Dilworth, Ronan P Hanley, Renato Ferreira de Freitas, et al.Journal of Chemical Information and Modeling|November 5, 2024
CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated ProteinFengling Li, Suzanne Ackloo, Cheryl H Arrowsmith, et al.Pageof 6