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The Journal of Biological Chemistry|November 14, 2014
Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small moleculeGejing Deng, Junqing Shen, Ming Yin, et al.
Oncoimmunology|September 6, 2021
Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using cross-over dual-variable domain (CODV) format for acute myeloid leukemia (AML) treatmentHélène Bonnevaux, Stephane Guerif, Jana Albrecht, et al.
Nature|February 24, 2022
A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cellsEdward Seung, Zhen Xing, Lan Wu, et al.
Molecular Cancer Research : MCR|March 12, 2015
Anti-miR-21 Suppresses Hepatocellular Carcinoma Growth via Broad Transcriptional Network DeregulationTimothy R Wagenaar, Sonya Zabludoff, Sung-Min Ahn, et al.
Oncoimmunology|November 10, 2022
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibodyJessica D Weaver, Edward C Stack, Joshua A Buggé, et al.
Scientific Reports|January 7, 2015
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodentsGuy Griebel, Philippe Pichat, Sandra Beeské, et al.
Cancer Cell|December 19, 2015
Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ DepletionKensuke Tateishi, Hiroaki Wakimoto, A John Iafrate, et al.
Science Translational Medicine|September 13, 2021
Local delivery of mRNA-encoded cytokines promotes antitumor immunity and tumor eradication across multiple preclinical tumor modelsChristian Hotz, Timothy R Wagenaar, Friederike Gieseke, et al.
Nature Cell Biology|October 21, 2014
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivoWilliam E Dowdle, Beat Nyfeler, Jane Nagel, et al.
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