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Iscience|May 11, 2026
An improved method for high-purity isolation of oligodendrocytes from neonatal and adult mouse brainPeiyi Guo, Elisabet Mandon, Jie Wang, et al.Molecular Therapy. Methods & Clinical Development|March 3, 2025
Cell-penetrating peptide-grafted AAV2 capsids for improved retinal delivery via intravitreal injectionJiang-Hui Wang, Mengtian Cui, Hao Liu, et al.Progress in Neurobiology|May 6, 2023
Renewal of oligodendrocyte lineage reverses dysmyelination and CNS neurodegeneration through corrected N-acetylaspartate metabolismAnoushka Lotun, Danning Li, Hongxia Xu, et al.Molecular Therapy. Methods & Clinical Development|May 17, 2018
A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in NeonatesDan Wang, Shaoyong Li, Dominic J Gessler, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|May 1, 2014
Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10Bin Yang, Shaoyong Li, Hongyan Wang, et al.Nature Communications|July 2, 2020
Structural characterization of a novel human adeno-associated virus capsid with neurotropic propertiesHung-Lun Hsu, Alexander Brown, Anna B Loveland, et al.Neuro-Oncology Advances|January 28, 2022
GammaTile® brachytherapy in the treatment of recurrent glioblastomasDominic J Gessler, Elizabeth C Neil, Rena Shah, et al.Nature Biotechnology|August 14, 2018
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in miceDan Wang, Jia Li, Chun-Qing Song, et al.Molecular Therapy. Methods & Clinical Development|August 21, 2023
Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulationManuela Corti, Barry J Byrne, Dominic J Gessler, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|May 7, 2025
Current clinical applications of AAV-mediated gene therapyBarry J Byrne, Kevin M Flanigan, Susan E Matesanz, et al.Pageof 2