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Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 12, 2025
Evaluation of small interfering RNA-dependent knockdowns of drug-metabolizing enzymes in multiwell array culture of primary human hepatocyte spheroids for estimation of fraction metabolizedLena Brücker, Dominik Jacob, Lena C Preiss, et al.
FEBS Letters|June 1, 2021
Binding and/or hydrolysis of purine-based nucleotides is not required for IM30 ring formationCarmen Siebenaller, Lukas Schlösser, Benedikt Junglas, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|November 10, 2025
<i>In vitro-in vivo</i> extrapolation of intrinsic clearance based on data from human hepatocyte spheroids - a case study with the low-clearance drug xevinapantDominik Jacob, Ulrike Gradhand, Christine K Maurer, et al.
Nucleic Acids Research|December 4, 2020
Bacterial tRNA 2'-O-methylation is dynamically regulated under stress conditions and modulates innate immune responseAdeline Galvanin, Lea-Marie Vogt, Antonia Grober, et al.
Angewandte Chemie (International Ed. in English)|March 21, 2019
Absolute Quantification of Noncoding RNA by Microscale ThermophoresisDominik Jacob, Kathrin Thüring, Aurellia Galliot, et al.
Nature Communications|June 19, 2021
Hakai is required for stabilization of core components of the m<sup>6</sup>A mRNA methylation machineryPraveen Bawankar, Tina Lence, Chiara Paolantoni, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 8, 2026
Mechanistically resolved prediction of compound hepatotoxicity using primary human liver spheroids-Application to recent real-world casesYufeng Li, Hongda Sheng, Tingting Zhou, et al.
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