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Current Pharmaceutical Design|February 4, 2012
Non-systemic drugs: a critical reviewDominique CharmotClinical Pharmacology in Drug Development|September 23, 2016
Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate BindersSusanne Johansson, Maria Leonsson-Zachrisson, Mikael Knutsson, et al.ACS Medicinal Chemistry Letters|July 21, 2022
Discovery of Tenapanor: A First-in-Class Minimally Systemic Inhibitor of Intestinal Na+/H+ Exchanger Isoform 3Jeffrey W Jacobs, Michael R Leadbetter, Noah Bell, et al.Stem Cell Reports|November 21, 2017
Development and Characterization of a Human and Mouse Intestinal Epithelial Cell Monolayer PlatformKenji Kozuka, Ying He, Samantha Koo-McCoy, et al.Science Translational Medicine|March 14, 2014
Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humansAndrew G Spencer, Eric D Labonte, David P Rosenbaum, et al.Journal of Medicinal Chemistry|August 25, 2018
Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5)Tao Chen, Nicholas William Reich, Noah Bell, et al.Journal of the American Society of Nephrology : JASN|November 19, 2014
Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKDEric D Labonté, Christopher W Carreras, Michael R Leadbetter, et al.Pageof 1