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Cancer Research|February 11, 2010
R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancerSacha J Holland, Alison Pan, Christian Franci, et al.
Antimicrobial Agents and Chemotherapy|January 30, 2008
Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replicationPeiyong Huang, Dane A Goff, Qi Huang, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 2, 2006
R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammationSylvia Braselmann, Vanessa Taylor, Haoran Zhao, et al.
Cancer Research|October 19, 2005
Multiple roles for the receptor tyrosine kinase axl in tumor formationSacha J Holland, Mark J Powell, Christian Franci, et al.
Blood|May 3, 2011
R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasmKotaro Shide, Takuro Kameda, Vadim Markovtsov, et al.
American Journal of Physiology. Heart and Circulatory Physiology|February 25, 2014
Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed miceKristen A Baltgalvis, Kathy White, Wei Li, et al.
Journal of Cancer Research and Clinical Oncology|July 18, 2009
Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screenJohn McLaughlin, Vadim Markovtsov, Hui Li, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|March 28, 2014
Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunctionIra J Smith, Guillermo L Godinez, Baljit K Singh, et al.
Plos One|December 17, 2013
AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetesYonchu Jenkins, Tian-Qiang Sun, Vadim Markovtsov, et al.
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