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Methods in Molecular Biology (Clifton, N.J.)|February 14, 2014
Case study 7. Compiled aha moments in enzyme kinetics: authors' experiencesDonald J Tweedie
Drug Metabolism and Disposition: the Biological Fate of Chemicals|June 17, 2015
Determination of a Degradation Constant for CYP3A4 by Direct Suppression of mRNA in a Novel Human Hepatocyte Model, HepatoPacDiane Ramsden, Jin Zhou, Donald J Tweedie
Methods in Molecular Biology (Clifton, N.J.)|February 14, 2014
Enzyme kinetics in drug metabolism: fundamentals and applicationsSwati Nagar, Upendra A Argikar, Donald J Tweedie
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 7, 2014
The role of transporters in toxicity and diseaseJohn D Schuetz, Peter W Swaan, Donald J Tweedie
Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 27, 2014
Altered CYP2C9 activity following modulation of CYP3A4 levels in human hepatocytes: an example of protein-protein interactionsDiane Ramsden, Donald J Tweedie, Tom S Chan, et al.
Drug Metabolism and Drug Interactions|October 30, 2013
Unexpected interaction between CYP3A4 and BI 11634: is BI 11634 interacting with CYP3A4 similar to nifedipine?Arti Mathur, Donald J Tweedie, Holly Hlaing-Hlaing Maw, et al.
Methods in Molecular Biology (Clifton, N.J.)|February 14, 2014
Case study 3. Application of basic enzyme kinetics to metabolism studies: real-life examplesYongmei Li, Michelle McCabe, Lalitha Podila, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 7, 2012
Metabolic switching of BILR 355 in the presence of ritonavir. II. Uncovering novel contributions by gut bacteria and aldehyde oxidaseYongmei Li, Jun Xu, W George Lai, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 25, 2013
Generating an in vitro-in vivo correlation for metabolism and liver enrichment of a hepatitis C virus drug, faldaprevir, using a rat hepatocyte model (HepatoPac)Diane Ramsden, Donald J Tweedie, Roger St George, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 25, 2013
Bridging in vitro and in vivo metabolism and transport of faldaprevir in human using a novel cocultured human hepatocyte system, HepatoPacDiane Ramsden, Donald J Tweedie, Tom S Chan, et al.
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