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Experimental Hematology|June 9, 2009
Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cuesHiroto Araki, Sudhakar Baluchamy, Kazumi Yoshinaga, et al.Haematologica|February 10, 2016
The LSD1 inhibitor RN-1 recapitulates the fetal pattern of hemoglobin synthesis in baboons (P. anubis)Angela Rivers, Kestis Vaitkus, Vinzon Ibanez, et al.Molecular Therapy. Methods & Clinical Development|March 11, 2020
The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin DisordersChristopher B Chambers, Jeffrey Gross, Katherine Pratt, et al.American Journal of Hematology|August 19, 2007
Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubisDonald Lavelle, Janet Chin, Kestis Vaitkus, et al.Journal of Translational Medicine|October 12, 2010
S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis)Donald Lavelle, Yogen Saunthararajah, Kestis Vaitkus, et al.British Journal of Haematology|March 23, 2011
Standard clinical practice underestimates the role and significance of erythropoietin deficiency in sickle cell diseaseSantosh Saraf, Mohammed Farooqui, Giovanni Infusino, et al.Experimental Hematology|August 21, 2018
Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboonsAngela Rivers, Kestis Vaitkus, Ramasamy Jagadeeswaran, et al.Experimental Hematology|February 28, 2017
Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell diseaseRamasamy Jagadeeswaran, Benjamin A Vazquez, Muthusamy Thiruppathi, et al.Blood|December 14, 2011
Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabineDonald Lavelle, Kestis Vaitkus, Yonghua Ling, et al.Blood|June 3, 2015
The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell miceShuaiying Cui, Kim-Chew Lim, Lihong Shi, et al.Pageof 4