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Experimental Hematology|November 5, 2013
NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human diseaseRachel Rau, Daniel Magoon, Sarah Greenblatt, et al.
Cancer Research|March 1, 2005
Inhibitory anti-FLT3 antibodies are capable of mediating antibody-dependent cell-mediated cytotoxicity and reducing engraftment of acute myelogenous leukemia blasts in nonobese diabetic/severe combined immunodeficient miceObdulio Piloto, Mark Levis, David Huso, et al.
Leukemia Research|August 2, 2011
A potential therapeutic target for FLT3-ITD AML: PIM1 kinaseAmir T Fathi, Omotayo Arowojolu, Ian Swinnen, et al.
Leukemia|June 30, 2025
SIRT5 inhibition impairs mitochondrial metabolism and enhances venetoclax-induced elimination of acute myeloid leukemia cellsMoran Wang, Ruiqi Zhu, Donald Small, et al.
Leukemia|May 29, 2024
Inhibition of NOTCH4 sensitizes FLT3/ITD acute myeloid leukemia cells to FLT3 tyrosine kinase inhibitionRuiqi Zhu, Courtney M Shirley, S Haihua Chu, et al.
Blood|April 23, 2016
All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivoHayley S Ma, Sarah M Greenblatt, Courtney M Shirley, et al.
Cell Stem Cell|January 21, 2014
Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenanceLev M Kats, Markus Reschke, Riccardo Taulli, et al.
Blood|July 22, 2006
Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitorsMark Levis, Patrick Brown, B Douglas Smith, et al.
Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation|June 18, 2013
Targeted pathologic evaluation of bone marrow donors identifies previously undiagnosed marrow abnormalitiesMatthew P Tilson, Richard J Jones, Amy Sexauer, et al.
Blood|April 24, 2004
Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibodyYiwen Li, Hongli Li, Mei-Nai Wang, et al.
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