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Douglas C Beshore

Showing results (11-20 of 24) with videos related to

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Bioorganic & Medicinal Chemistry Letters|March 30, 2010
Hydroxy cycloalkyl fused pyridone carboxylic acid M(1) positive allosteric modulatorsScott D Kuduk, Robert M DiPardo, Douglas C Beshore, et al.
Bioorganic & Medicinal Chemistry Letters|February 4, 2014
Identification of a methoxynaphthalene scaffold as a core replacement in quinolizidinone amide M(1) positive allosteric modulatorsScott D Kuduk, Christina N Di Marco, Jonathan R Saffold, et al.
SLAS Discovery : Advancing Life Sciences R & D|April 21, 2017
High-Throughput Agonist Shift Assay Development for the Analysis of M<sub>1</sub>-Positive Allosteric ModulatorsMichelle F Homsher, Douglas C Beshore, Jason Cassaday, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 18, 2018
Microbial biotransformation - an important tool for the study of drug metabolismRhys Salter, Douglas C Beshore, Steven L Colletti, et al.
ACS Medicinal Chemistry Letters|July 24, 2018
MK-7622: A First-in-Class M<sub>1</sub> Positive Allosteric Modulator Development CandidateDouglas C Beshore, Christina N Di Marco, Ronald K Chang, et al.
Communications Biology|June 19, 2023
Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerasesVictoria A Kleiner, Thierry O Fischmann, John A Howe, et al.
Journal of Medicinal Chemistry|April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity ProfilesJohn M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
ACS Medicinal Chemistry Letters|April 15, 2021
Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor InteractionDouglas C Beshore, Gregory C Adam, Richard J O Barnard, et al.
Bioorganic & Medicinal Chemistry Letters|March 23, 2010
Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channelDouglas C Beshore, Nigel J Liverton, Charles J McIntyre, et al.
Journal of Medicinal Chemistry|November 28, 2006
Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillationB Wesley Trotter, Kausik K Nanda, Nathan R Kett, et al.
Pageof 3

Showing results (11-20 of 24) with videos related to

Sort By:
Pageof 3
Bioorganic & Medicinal Chemistry Letters|March 30, 2010
Hydroxy cycloalkyl fused pyridone carboxylic acid M(1) positive allosteric modulatorsScott D Kuduk, Robert M DiPardo, Douglas C Beshore, et al.
Bioorganic & Medicinal Chemistry Letters|February 4, 2014
Identification of a methoxynaphthalene scaffold as a core replacement in quinolizidinone amide M(1) positive allosteric modulatorsScott D Kuduk, Christina N Di Marco, Jonathan R Saffold, et al.
SLAS Discovery : Advancing Life Sciences R & D|April 21, 2017
High-Throughput Agonist Shift Assay Development for the Analysis of M<sub>1</sub>-Positive Allosteric ModulatorsMichelle F Homsher, Douglas C Beshore, Jason Cassaday, et al.
Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 18, 2018
Microbial biotransformation - an important tool for the study of drug metabolismRhys Salter, Douglas C Beshore, Steven L Colletti, et al.
ACS Medicinal Chemistry Letters|July 24, 2018
MK-7622: A First-in-Class M<sub>1</sub> Positive Allosteric Modulator Development CandidateDouglas C Beshore, Christina N Di Marco, Ronald K Chang, et al.
Communications Biology|June 19, 2023
Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerasesVictoria A Kleiner, Thierry O Fischmann, John A Howe, et al.
Journal of Medicinal Chemistry|April 19, 2017
Informing the Selection of Screening Hit Series with in Silico Absorption, Distribution, Metabolism, Excretion, and Toxicity ProfilesJohn M Sanders, Douglas C Beshore, J Christopher Culberson, et al.
ACS Medicinal Chemistry Letters|April 15, 2021
Redefining the Histone Deacetylase Inhibitor Pharmacophore: High Potency with No Zinc Cofactor InteractionDouglas C Beshore, Gregory C Adam, Richard J O Barnard, et al.
Bioorganic & Medicinal Chemistry Letters|March 23, 2010
Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channelDouglas C Beshore, Nigel J Liverton, Charles J McIntyre, et al.
Journal of Medicinal Chemistry|November 28, 2006
Design and synthesis of novel isoquinoline-3-nitriles as orally bioavailable Kv1.5 antagonists for the treatment of atrial fibrillationB Wesley Trotter, Kausik K Nanda, Nathan R Kett, et al.
Pageof 3