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The Journal of Clinical Investigation|September 22, 2012
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progressionAndreas Weiss, Ulrike Träger, Edward J Wild, et al.
Plos One|April 8, 2022
Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validationDavid F Fischer, Sipke Dijkstra, Kimberly Lo, et al.
Plos One|December 3, 2014
Polyglutamine- and temperature-dependent conformational rigidity in mutant huntingtin revealed by immunoassays and circular dichroism spectroscopyValentina Fodale, Natalie C Kegulian, Margherita Verani, et al.
Molecular Cancer Therapeutics|August 10, 2019
Preclinical Development of the Anti-LAG-3 Antibody REGN3767: Characterization and Activity in Combination with the Anti-PD-1 Antibody Cemiplimab in Human PD-1xLAG-3-Knockin MiceElena Burova, Aynur Hermann, Jie Dai, et al.
Scientific Reports|December 15, 2015
A novel, native-format bispecific antibody triggering T-cell killing of B-cells is robustly active in mouse tumor models and cynomolgus monkeysEric J Smith, Kara Olson, Lauric J Haber, et al.
Molecular Cancer Therapeutics|March 18, 2014
ERBB3/HER2 signaling promotes resistance to EGFR blockade in head and neck and colorectal cancer modelsLi Zhang, Carla Castanaro, Bo Luan, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
SAR Development of Lysine-Based Irreversible Inhibitors of Transglutaminase 2 for Huntington's DiseaseJohn Wityak, Michael E Prime, Frederick A Brookfield, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 19, 2019
A Biparatopic Antibody That Modulates MET Trafficking Exhibits Enhanced Efficacy Compared with Parental Antibodies in MET-Driven Tumor ModelsJohn O DaSilva, Katie Yang, Andres E Perez Bay, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's DiseaseMichael E Prime, Frederick A Brookfield, Stephen M Courtney, et al.
Plos One|March 27, 2019
Meso scale discovery-based assays for the detection of aggregated huntingtinWolfgang Reindl, Barbara Baldo, Jana Schulz, et al.
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