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ACS Medicinal Chemistry Letters|January 25, 2021
Discovery of a Series of Pyrazinone RORγ Antagonists and Identification of the Clinical Candidate BI 730357Christian Harcken, Johanna Csengery, Michael Turner, et al.Frontiers in Immunology|November 9, 2018
An RORγt Oral Inhibitor Modulates IL-17 Responses in Peripheral Blood and Intestinal Mucosa of Crohn's Disease PatientsHelena Bassolas-Molina, Ernest Raymond, Mark Labadia, et al.Nature Communications|January 4, 2019
RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patientsKoen Venken, Peggy Jacques, Céline Mortier, et al.Proceedings of the National Academy of Sciences of the United States of America|October 10, 2018
Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1)Marcin Kowanetz, Wei Zou, Scott N Gettinger, et al.Bioorganic & Medicinal Chemistry Letters|December 22, 2015
Late-stage optimization of a tercyclic class of S1P3-sparing, S1P1 receptor agonistsJoshua C Horan, Daniel Kuzmich, Pingrong Liu, et al.Pageof 4