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E Allen Sickmier

Showing results (11-20 of 23) with videos related to

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Plos One|June 11, 2019
Correction: Crystal structures of human procathepsin HYue Hao, Whitney E Purtha, Christa Cortesio, et al.
SLAS Discovery : Advancing Life Sciences R & D|August 25, 2023
Development of assays to support identification and characterization of modulators of DExH-box helicase DHX9Deepali Gotur, April Case, Julie Liu, et al.
Medchemcomm|August 16, 2018
Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin DJonathan D Low, Michael D Bartberger, Kui Chen, et al.
Structure (London, England : 1993)|May 23, 2017
Structural Basis for Apelin Control of the Human Apelin ReceptorYingli Ma, Yang Yue, Yanbin Ma, et al.
Journal of Medicinal Chemistry|August 20, 2015
Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3Justin K Murray, Yi-Xin Qian, Benxian Liu, et al.
ACS Chemical Biology|July 20, 2016
Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-DehydrataseJohn G Allen, Mirna Mujacic, Michael J Frohn, et al.
Journal of Medicinal Chemistry|June 29, 2011
From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)Yuan Cheng, Ted C Judd, Michael D Bartberger, et al.
Journal of Medicinal Chemistry|April 29, 2025
Discovery of ATX968: An Orally Available Allosteric Inhibitor of DHX9Matthew H Daniels, Jennifer Castro, Young-Tae Lee, et al.
Communications Biology|April 9, 2025
Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitorGordon J Lockbaum, Maureen M Lynes, Sophie A Shen, et al.
Cancer Research|November 26, 2024
A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch RepairJennifer Castro, Matthew H Daniels, David Brennan, et al.
Pageof 3

Showing results (11-20 of 23) with videos related to

Sort By:
Pageof 3
Plos One|June 11, 2019
Correction: Crystal structures of human procathepsin HYue Hao, Whitney E Purtha, Christa Cortesio, et al.
SLAS Discovery : Advancing Life Sciences R & D|August 25, 2023
Development of assays to support identification and characterization of modulators of DExH-box helicase DHX9Deepali Gotur, April Case, Julie Liu, et al.
Medchemcomm|August 16, 2018
Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin DJonathan D Low, Michael D Bartberger, Kui Chen, et al.
Structure (London, England : 1993)|May 23, 2017
Structural Basis for Apelin Control of the Human Apelin ReceptorYingli Ma, Yang Yue, Yanbin Ma, et al.
Journal of Medicinal Chemistry|August 20, 2015
Pharmaceutical Optimization of Peptide Toxins for Ion Channel Targets: Potent, Selective, and Long-Lived Antagonists of Kv1.3Justin K Murray, Yi-Xin Qian, Benxian Liu, et al.
ACS Chemical Biology|July 20, 2016
Facile Modulation of Antibody Fucosylation with Small Molecule Fucostatin Inhibitors and Cocrystal Structure with GDP-Mannose 4,6-DehydrataseJohn G Allen, Mirna Mujacic, Michael J Frohn, et al.
Journal of Medicinal Chemistry|June 29, 2011
From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)Yuan Cheng, Ted C Judd, Michael D Bartberger, et al.
Journal of Medicinal Chemistry|April 29, 2025
Discovery of ATX968: An Orally Available Allosteric Inhibitor of DHX9Matthew H Daniels, Jennifer Castro, Young-Tae Lee, et al.
Communications Biology|April 9, 2025
Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitorGordon J Lockbaum, Maureen M Lynes, Sophie A Shen, et al.
Cancer Research|November 26, 2024
A Potent, Selective, Small-Molecule Inhibitor of DHX9 Abrogates Proliferation of Microsatellite Instable Cancers with Deficient Mismatch RepairJennifer Castro, Matthew H Daniels, David Brennan, et al.
Pageof 3