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Ebiomedicine|March 27, 2019
Tau antibody chimerization alters its charge and binding, thereby reducing its cellular uptake and efficacyErin E Congdon, Jessica E Chukwu, Dov B Shamir, et al.
Biorxiv : the Preprint Server for Biology|July 9, 2025
Single-Domain Antibody-Based Autophagosome-Targeting Chimera for Tau Clearance and Motor Function Restoration in TauopathiesYixiang Jiang, Amber M Tetlow, Yan Lin, et al.
Science Translational Medicine|April 15, 2026
Autophagosome-targeting single-domain antibody clears tau in patient-derived neurons and improves motor function in tauopathy miceYixiang Jiang, Amber M Tetlow, Yan Lin, et al.
Science Advances|May 10, 2023
Single-domain antibody-based noninvasive in vivo imaging of α-synuclein or tau pathologyYixiang Jiang, Yan Lin, Senthilkumar Krishnaswamy, et al.
Autophagy|February 25, 2012
Methylthioninium chloride (methylene blue) induces autophagy and attenuates tauopathy in vitro and in vivoErin E Congdon, Jessica W Wu, Natura Myeku, et al.
Molecular Neurodegeneration|September 1, 2016
Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacyErin E Congdon, Yan Lin, Hameetha B Rajamohamedsait, et al.
Biorxiv : the Preprint Server for Biology|August 5, 2026
A single-domain antibody targets aggregation-prone region of α-synuclein to reduce synucleinopathy, rescue neurodegeneration and improve functionPragati, Erin E Congdon, Yixiang Jiang, et al.
Cell Reports|September 18, 2025
Clearing truncated tau protein restores neuronal function and prevents microglia activation in tauopathy miceAlejandro Martín-Ávila, Swananda R Modak, Hameetha B Rajamohamedsait, et al.
Scientific Data|December 7, 2016
A phenome-wide examination of neural and cognitive functionR A Poldrack, E Congdon, W Triplett, et al.
Molecular Neurodegeneration|November 3, 2010
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burdenJohn C O'Leary, Qingyou Li, Paul Marinec, et al.
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