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Journal of Controlled Release : Official Journal of the Controlled Release Society|April 7, 2023
High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivoSebastian G Huayamares, Melissa P Lokugamage, Regina Rab, et al.
Cell|September 30, 2014
CRISPR-Cas9 knockin mice for genome editing and cancer modelingRandall J Platt, Sidi Chen, Yang Zhou, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 4, 2024
Cationic cholesterol-dependent LNP delivery to lung stem cells, the liver, and heartAfsane Radmand, Hyejin Kim, Jared Beyersdorf, et al.
Blood Advances|January 17, 2025
Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAsNoa A Linthorst, Yvonne K Jongejan, Richard J Dirven, et al.
Nature Chemistry|March 2, 2023
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA deliveryMarine Z C Hatit, Curtis N Dobrowolski, Melissa P Lokugamage, et al.
Nature Communications|April 12, 2025
Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responsesSebastian G Huayamares, Liming Lian, Regina Rab, et al.
Science Translational Medicine|June 10, 2016
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarctionHendrik B Sager, Partha Dutta, James E Dahlman, et al.
Nature Metabolism|October 2, 2019
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosisPei-Yu Chen, Lingfeng Qin, Guangxin Li, et al.
The Journal of Clinical Investigation|April 27, 2021
Frataxin deficiency promotes endothelial senescence in pulmonary hypertensionMiranda K Culley, Jingsi Zhao, Yi Yin Tai, et al.
EMBO Molecular Medicine|April 1, 2015
Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertensionKevin White, Yu Lu, Sofia Annis, et al.
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