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Mabs|May 28, 2016
Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodiesLindsay B Avery, Mengmeng Wang, Mania S Kavosi, et al.Journal of Medicinal Chemistry|July 21, 2006
Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approachXinrong Tian, Timothy B Field, Adrian G Switzer, et al.Journal of Inflammation (London, England)|August 13, 2010
Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritisDebra M Meyer, Michael I Jesson, Xiong Li, et al.Journal of Medicinal Chemistry|February 12, 2000
Design and synthesis of piperazine-based matrix metalloproteinase inhibitorsM Cheng, B De, S Pikul, et al.Bioorganic & Medicinal Chemistry Letters|November 17, 2006
Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERGKenneth M Meyers, José L Méndez-Andino, Anny-Odile Colson, et al.Bioorganic & Medicinal Chemistry|January 24, 2007
The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: a novel class of potent MCH-R1 antagonistsJosé L Méndez-Andino, Anny-Odile Colson, Kenneth M Meyers, et al.Clinical Pharmacology and Therapeutics|October 18, 2024
Building Confidence in Physiologically Based Pharmacokinetic Modeling of CYP3A Induction Mediated by Rifampin: An Industry PerspectiveMicaela B Reddy, Tamara D Cabalu, Loeckie de Zwart, et al.Journal of Immunology (Baltimore, Md. : 1950)|March 9, 2011
Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550)Kamran Ghoreschi, Michael I Jesson, Xiong Li, et al.Bioorganic & Medicinal Chemistry|April 8, 2020
Design and optimization of a series of 4-(3-azabicyclo[3.1.0]hexan-3-yl)pyrimidin-2-amines: Dual inhibitors of TYK2 and JAK1Andrew Fensome, Catherine M Ambler, Eric Arnold, et al.Journal of Medicinal Chemistry|September 6, 2008
Discovery of orally bioavailable 1,3,4-trisubstituted 2-oxopiperazine-based melanocortin-4 receptor agonists as potential antiobesity agentsXinrong Tian, Adrian G Switzer, Steve A Derose, et al.Pageof 6