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Toxicology and Applied Pharmacology|April 23, 2023
The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient miceAndrea C Postmus, Janine K Kruit, Roos E Eilers, et al.Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie|January 21, 2023
Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expressionCristy R C Verzijl, Ivo P van de Peppel, Roos E Eilers, et al.Gastro Hep Advances|March 2, 2026
Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative PhosphorylationCristy R C Verzijl, Dicky Struik, Albert Gerding, et al.Cellular and Molecular Gastroenterology and Hepatology|October 9, 2021
Defective Lipid Droplet-Lysosome Interaction Causes Fatty Liver Disease as Evidenced by Human Mutations in TMEM199 and CCDC115Lars E Larsen, Marjolein A W van den Boogert, Wilson A Rios-Ocampo, et al.Pageof 7