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Scientific Reports|December 23, 2025
Probing the activity of cysteine cathepsins in inflammatory bowel diseasesBethany M Anderson, Alexander R Ziegler, Rhiannon I Campden, et al.
Neurogastroenterology and Motility|July 11, 2019
The impact of dietary fermentable carbohydrates on a postinflammatory model of irritable bowel syndromeCaroline J Tuck, Alberto Caminero, Nestor N Jiménez Vargas, et al.
Biorxiv : the Preprint Server for Biology|January 27, 2025
Identification of a secreted protease from Bacteroides fragilis that induces intestinal pain and inflammation by cleavage of PAR2Markus Lakemeyer, Rocco Latorre, Kristyna Blazkova, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|November 21, 2025
Electrophysiological and proteomic evidence of protease-mediated pro-nociceptive signaling in inflammatory bowel disease patientsHannah M Wood, Amal Abu Omar, Corey C Baker, et al.
Cell Host & Microbe|September 27, 2025
A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammationMarkus Lakemeyer, Rocco Latorre, Kristyna Blazkova, et al.
Cellular and Molecular Gastroenterology and Hepatology|March 17, 2024
Protease-Induced Excitation of Dorsal Root Ganglion Neurons in Response to Acute Perturbation of the Gut Microbiota Is Associated With Visceral and Somatic HypersensitivityCorey C Baker, Jessica L Sessenwein, Hannah M Wood, et al.
Gut|January 2, 2023
Changes in signalling from faecal neuroactive metabolites following dietary modulation of IBS painCaroline J Tuck, Amal Abu Omar, Giada De Palma, et al.
Gastroenterology|February 20, 2025
Psychological Stress-Induced Local Immune Response to Food Antigens Increases Pain Signaling Across the Gut in MiceJavier Aguilera-Lizarraga, Cintya Lopez-Lopez, Josue Jaramillo-Polanco, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 18, 2020
Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory painNestor N Jimenez-Vargas, Jing Gong, Matthew J Wisdom, et al.
Science Translational Medicine|July 27, 2022
Histamine production by the gut microbiota induces visceral hyperalgesia through histamine 4 receptor signaling in miceGiada De Palma, Chiko Shimbori, David E Reed, et al.
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