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Journal for Immunotherapy of Cancer|July 15, 2026
Sleeping Beauty mutagenesis identifies BACH2 and other regulators of CD8+ T-cell exhaustion, persistence in vivo, and CAR-T cell function under tumor-associated chronic antigen stimulationChang-Jung Lee, Alex T Larsson, Tyler A Jubenville, et al.Bioorganic & Medicinal Chemistry Letters|January 29, 2011
Diamide amino-imidazoles: a novel series of γ-secretase inhibitors for the treatment of Alzheimer's diseaseMichael A Brodney, David D Auperin, Stacey L Becker, et al.Bioorganic & Medicinal Chemistry Letters|January 29, 2011
Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: discovery of PF-3084014Michael A Brodney, David D Auperin, Stacey L Becker, et al.Journal of Medicinal Chemistry|April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking HypopigmentationBrian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.Angewandte Chemie (International Ed. in English)|June 30, 2016
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET NeuroimagingSteven H Liang, Jinshan Michael Chen, Marc D Normandin, et al.Frontiers in Artificial Intelligence|March 17, 2023
First Organoid Intelligence (OI) workshop to form an OI communityItzy E Morales Pantoja, Lena Smirnova, Alysson R Muotri, et al.The Journal of Experimental Medicine|May 5, 2021
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patientsCarole Le Coz, David N Nguyen, Chun Su, et al.Blood|January 24, 2025
One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying themAinsley V C Knox, Lauren Y Cominsky, Di Sun, et al.Pageof 55