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E Nolan

Showing results (311-320 of 327) with videos related to

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The Journal of Allergy and Clinical Immunology|June 24, 2018
Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responsesNeil Romberg, Carole Le Coz, Salomé Glauzy, et al.
Journal of Virology|December 28, 2007
High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcomeVictoria Kasprowicz, Julian Schulze Zur Wiesch, Thomas Kuntzen, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 6, 2010
Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014Thomas A Lanz, Kathleen M Wood, Karl E G Richter, et al.
Journal of Medicinal Chemistry|December 21, 2016
Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide FunctionalityChristopher R Butler, Kevin Ogilvie, Luis Martinez-Alsina, et al.
Nature Communications|October 12, 2016
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitorsAndrea M Zuhl, Charles E Nolan, Michael A Brodney, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 22, 2006
Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139Thomas A Lanz, Michael J Karmilowicz, Kathleen M Wood, et al.
Journal of Medicinal Chemistry|February 20, 2015
Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug designChristopher R Butler, Michael A Brodney, Elizabeth M Beck, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 13, 2012
Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancerCharles M Rudin, Christine L Hann, Edward B Garon, et al.
Journal of Medicinal Chemistry|October 15, 2011
Metabolism-directed design of oxetane-containing arylsulfonamide derivatives as γ-secretase inhibitorsAntonia F Stepan, Kapil Karki, W Scott McDonald, et al.
Journal of Medicinal Chemistry|March 17, 2012
Application of the bicyclo[1.1.1]pentane motif as a nonclassical phenyl ring bioisostere in the design of a potent and orally active γ-secretase inhibitorAntonia F Stepan, Chakrapani Subramanyam, Ivan V Efremov, et al.
Pageof 33

Showing results (311-320 of 327) with videos related to

Sort By:
Pageof 33
The Journal of Allergy and Clinical Immunology|June 24, 2018
Patients with common variable immunodeficiency with autoimmune cytopenias exhibit hyperplastic yet inefficient germinal center responsesNeil Romberg, Carole Le Coz, Salomé Glauzy, et al.
Journal of Virology|December 28, 2007
High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcomeVictoria Kasprowicz, Julian Schulze Zur Wiesch, Thomas Kuntzen, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 6, 2010
Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014Thomas A Lanz, Kathleen M Wood, Karl E G Richter, et al.
Journal of Medicinal Chemistry|December 21, 2016
Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide FunctionalityChristopher R Butler, Kevin Ogilvie, Luis Martinez-Alsina, et al.
Nature Communications|October 12, 2016
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitorsAndrea M Zuhl, Charles E Nolan, Michael A Brodney, et al.
The Journal of Pharmacology and Experimental Therapeutics|August 22, 2006
Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139Thomas A Lanz, Michael J Karmilowicz, Kathleen M Wood, et al.
Journal of Medicinal Chemistry|February 20, 2015
Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug designChristopher R Butler, Michael A Brodney, Elizabeth M Beck, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|April 13, 2012
Phase II study of single-agent navitoclax (ABT-263) and biomarker correlates in patients with relapsed small cell lung cancerCharles M Rudin, Christine L Hann, Edward B Garon, et al.
Journal of Medicinal Chemistry|October 15, 2011
Metabolism-directed design of oxetane-containing arylsulfonamide derivatives as γ-secretase inhibitorsAntonia F Stepan, Kapil Karki, W Scott McDonald, et al.
Journal of Medicinal Chemistry|March 17, 2012
Application of the bicyclo[1.1.1]pentane motif as a nonclassical phenyl ring bioisostere in the design of a potent and orally active γ-secretase inhibitorAntonia F Stepan, Chakrapani Subramanyam, Ivan V Efremov, et al.
Pageof 33