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Showing results (321-330 of 327) with videos related to

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Journal of Medicinal Chemistry|March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitorsMichael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Bioorganic & Medicinal Chemistry Letters|January 29, 2011
Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: discovery of PF-3084014Michael A Brodney, David D Auperin, Stacey L Becker, et al.
Bioorganic & Medicinal Chemistry Letters|January 29, 2011
Diamide amino-imidazoles: a novel series of γ-secretase inhibitors for the treatment of Alzheimer's diseaseMichael A Brodney, David D Auperin, Stacey L Becker, et al.
Journal of Medicinal Chemistry|April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking HypopigmentationBrian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Angewandte Chemie (International Ed. in English)|June 30, 2016
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET NeuroimagingSteven H Liang, Jinshan Michael Chen, Marc D Normandin, et al.
The Journal of Experimental Medicine|May 5, 2021
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patientsCarole Le Coz, David N Nguyen, Chun Su, et al.
Blood|January 24, 2025
One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying themAinsley V C Knox, Lauren Y Cominsky, Di Sun, et al.
Pageof 33

Showing results (321-330 of 327) with videos related to

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Pageof 33
You have reached the last page of results.This site can display upto 327 results.
Journal of Medicinal Chemistry|March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitorsMichael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Bioorganic & Medicinal Chemistry Letters|January 29, 2011
Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: discovery of PF-3084014Michael A Brodney, David D Auperin, Stacey L Becker, et al.
Bioorganic & Medicinal Chemistry Letters|January 29, 2011
Diamide amino-imidazoles: a novel series of γ-secretase inhibitors for the treatment of Alzheimer's diseaseMichael A Brodney, David D Auperin, Stacey L Becker, et al.
Journal of Medicinal Chemistry|April 4, 2018
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking HypopigmentationBrian T O'Neill, Elizabeth M Beck, Christopher R Butler, et al.
Angewandte Chemie (International Ed. in English)|June 30, 2016
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET NeuroimagingSteven H Liang, Jinshan Michael Chen, Marc D Normandin, et al.
The Journal of Experimental Medicine|May 5, 2021
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patientsCarole Le Coz, David N Nguyen, Chun Su, et al.
Blood|January 24, 2025
One hundred thirty-four germ line PU.1 variants and the agammaglobulinemic patients carrying themAinsley V C Knox, Lauren Y Cominsky, Di Sun, et al.
Pageof 33