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Biochemical Pharmacology|November 6, 2008
Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrinDongfang Yang, Robin E Pearce, Xiliang Wang, et al.
American Journal of Obstetrics and Gynecology|January 14, 2014
Uterine cellular leiomyomata with chromosome 1p deletions represent a distinct entityJennelle C Hodge, Kathryn E Pearce, Amy C Clayton, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 23, 2021
Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of LiverJ Steven Leeder, Jean C Dinh, Andrea Gaedigk, et al.
Toxicology Letters|January 12, 2000
Effects of musk xylene and musk ketone on rat hepatic cytochrome P450 enzymesL D Lehman-McKeeman, D Caudill, J D Vassallo, et al.
Clinical Therapeutics|October 9, 2008
Six-month, prospective, longitudinal, open-label caffeine and dextromethorphan phenotyping study in children with growth hormone deficiency receiving recombinant human growth hormone replacementMary Jayne Kennedy, Daniel A Davis, Ned Smith, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 9, 2008
Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepineRobin E Pearce, Wei Lu, Yongqiang Wang, et al.
JCO Precision Oncology|January 26, 2023
First-in-Human Study of OBI-999, a Globo H-Targeting Antibody-Drug Conjugate, in Patients With Advanced Solid TumorsApostolia Maria Tsimberidou, Henry Hiep Vo, Jennifer Beck, et al.
Muscle & Nerve|December 16, 2024
Mortality Trends and Causes of Death in Myotonic Dystrophy Type 1 Patients From the UK Clinical Practice Research DatalinkRotana Alsaggaf, Ruth M Pfeiffer, Emily E Pearce, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 16, 2002
Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquineKenda A Marcucci, Robin E Pearce, Charles Crespi, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|December 22, 2007
CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profilePing Kang, Mingxiang Liao, Michael R Wester, et al.
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