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The Journal of Biological Chemistry|August 27, 2010
Epigenetic silencing of beta-spectrin, a TGF-beta signaling/scaffolding protein in a human cancer stem cell disorder: Beckwith-Wiedemann syndromeZhi-Xing Yao, Wilma Jogunoori, Sanaa Choufani, et al.
Hepatology (Baltimore, Md.)|April 27, 2011
Transforming growth factor-β adaptor, β2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancerHye Jung Baek, Michael J Pishvaian, Yi Tang, et al.
Cell Reports. Medicine|July 8, 2025
Unlocking the therapeutic potential of rigosertib as a selective therapy for ovarian cancerShalini Nath, Sally Claridge, Genesis Lara Granados, et al.
Nature Communications|August 4, 2021
Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant diseaseKatsutoshi Sato, Amol A Padgaonkar, Stacey J Baker, et al.
Journal of Medicinal Chemistry|January 15, 2014
Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5)M V Ramana Reddy, Balireddy Akula, Stephen C Cosenza, et al.
Bioorganic & Medicinal Chemistry|January 15, 2016
Discovery of 2-(1H-indol-5-ylamino)-6-(2,4-difluorophenylsulfonyl)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one (7ao) as a potent selective inhibitor of Polo like kinase 2 (PLK2)M V Ramana Reddy, Balireddy Akula, Shashidhar Jatiani, et al.
Cell|April 23, 2016
A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block SignalingSai Krishna Athuluri-Divakar, Rodrigo Vasquez-Del Carpio, Kaushik Dutta, et al.
Pharmacological Reviews|March 27, 2025
Cell cycle dysregulation in cancerAntonino Glaviano, Samarendra K Singh, E Hui Clarissa Lee, et al.
Cell Stem Cell|February 21, 2017
Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable LeukemiaAndriana G Kotini, Chan-Jung Chang, Arthur Chow, et al.
Cancer Discovery|September 7, 2023
Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate CancerSandra Santasusagna, Shijia Zhu, Vijayakumar Jawalagatti, et al.
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