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The Journal of Pharmacology and Experimental Therapeutics|November 21, 2007
Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathwayJeffrey F Waring, Yi Yang, Christine H Healan-Greenberg, et al.ACS Chemical Biology|July 9, 2024
Quantitative Measurement of Rate of Targeted Protein DegradationThomas L Lynch, Violeta L Marin, Ryan A McClure, et al.ACS Chemical Biology|February 21, 2022
The HPK1 Inhibitor A-745 Verifies the Potential of Modulating T Cell Kinase Signaling for ImmunotherapySven Malchow, Alla Korepanova, Sanjay C Panchal, et al.Cell Chemical Biology|October 7, 2025
Discovery of a tau-aggregate clearing compound that covalently targets P4HBLouis P Conway, Michelle A Estrada, Weichao Li, et al.Cancer Research|April 19, 2017
Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic StrategiesMai H Bui, Xiaoyu Lin, Daniel H Albert, et al.Cell Chemical Biology|July 2, 2026
Mechanistic dissection of SMARCA2/4 molecular glues reveals programmable switching between DCAF16 and FBXO22Milad Rouhimoghadam, Christie J Kang, Jackson A Gartman, et al.Bioorganic & Medicinal Chemistry Letters|March 8, 2017
Methylpyrrole inhibitors of BET bromodomainsLisa A Hasvold, George S Sheppard, Le Wang, et al.Journal of Medicinal Chemistry|September 27, 2017
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain InhibitorKeith F McDaniel, Le Wang, Todd Soltwedel, et al.Journal of Medicinal Chemistry|April 4, 2017
Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain InhibitorsLe Wang, John K Pratt, Todd Soltwedel, et al.Pageof 4