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Eddine Saiah

Showing results (11-20 of 31) with videos related to

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The Journal of Clinical Investigation|April 17, 2019
Sestrin modulator NV-5138 produces rapid antidepressant effects via direct mTORC1 activationTaro Kato, Santosh Pothula, Rong-Jian Liu, et al.
Drug Metabolism Letters|January 5, 2011
Comparative pharmacokinetics and metabolism studies in lean and diet- induced obese mice: an animal efficacy model for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitorsMengmeng Wang, Xianbin Tian, Louis Leung, et al.
The Journal of Organic Chemistry|July 9, 2011
Synthesis of potent and orally efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitor HSD-016Zhao-Kui Wan, Eva Chenail, Huan-Qiu Li, et al.
Journal of Molecular Graphics & Modelling|June 20, 2002
Coupling structure-based design with combinatorial chemistry: application of active site derived pharmacophores with informative library designJohn E Eksterowicz, Erik Evensen, Christian Lemmen, et al.
Journal of Medicinal Chemistry|June 2, 2012
Diazine indole acetic acids as potent, selective, and orally bioavailable antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseasesNeelu Kaila, Adrian Huang, Alessandro Moretto, et al.
Cell Chemical Biology|June 25, 2019
Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose TransportersSeong A Kang, David J O'Neill, Andreas W Machl, et al.
Bioorganic & Medicinal Chemistry Letters|March 13, 2013
Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitorE Scott Priestley, Indawati De Lucca, Jinglan Zhou, et al.
Journal of Medicinal Chemistry|February 12, 2014
Discovery of isoquinolinone indole acetic acids as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseasesNeelu Kaila, Bruce Follows, Louis Leung, et al.
Bioorganic & Medicinal Chemistry Letters|March 6, 2007
Probing acid replacements of thiophene PTP1B inhibitorsZhao-Kui Wan, Bruce Follows, Steve Kirincich, et al.
Journal of Medicinal Chemistry|June 27, 2008
Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia modelJason Xiang, Zhao-Kui Wan, Huan-Qiu Li, et al.
Pageof 4

Showing results (11-20 of 31) with videos related to

Sort By:
Pageof 4
The Journal of Clinical Investigation|April 17, 2019
Sestrin modulator NV-5138 produces rapid antidepressant effects via direct mTORC1 activationTaro Kato, Santosh Pothula, Rong-Jian Liu, et al.
Drug Metabolism Letters|January 5, 2011
Comparative pharmacokinetics and metabolism studies in lean and diet- induced obese mice: an animal efficacy model for 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitorsMengmeng Wang, Xianbin Tian, Louis Leung, et al.
The Journal of Organic Chemistry|July 9, 2011
Synthesis of potent and orally efficacious 11β-hydroxysteroid dehydrogenase type 1 inhibitor HSD-016Zhao-Kui Wan, Eva Chenail, Huan-Qiu Li, et al.
Journal of Molecular Graphics & Modelling|June 20, 2002
Coupling structure-based design with combinatorial chemistry: application of active site derived pharmacophores with informative library designJohn E Eksterowicz, Erik Evensen, Christian Lemmen, et al.
Journal of Medicinal Chemistry|June 2, 2012
Diazine indole acetic acids as potent, selective, and orally bioavailable antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseasesNeelu Kaila, Adrian Huang, Alessandro Moretto, et al.
Cell Chemical Biology|June 25, 2019
Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose TransportersSeong A Kang, David J O'Neill, Andreas W Machl, et al.
Bioorganic & Medicinal Chemistry Letters|March 13, 2013
Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitorE Scott Priestley, Indawati De Lucca, Jinglan Zhou, et al.
Journal of Medicinal Chemistry|February 12, 2014
Discovery of isoquinolinone indole acetic acids as antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseasesNeelu Kaila, Bruce Follows, Louis Leung, et al.
Bioorganic & Medicinal Chemistry Letters|March 6, 2007
Probing acid replacements of thiophene PTP1B inhibitorsZhao-Kui Wan, Bruce Follows, Steve Kirincich, et al.
Journal of Medicinal Chemistry|June 27, 2008
Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia modelJason Xiang, Zhao-Kui Wan, Huan-Qiu Li, et al.
Pageof 4