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Advances in Experimental Medicine and Biology|April 11, 2020
Heparanase Inhibition by Pixatimod (PG545): Basic Aspects and Future PerspectivesEdward Hammond, Keith DredgePlos One|January 10, 2013
PG545, a heparan sulfate mimetic, reduces heparanase expression in vivo, blocks spontaneous metastases and enhances overall survival in the 4T1 breast carcinoma modelEdward Hammond, Ralf Brandt, Keith DredgeFEBS Open Bio|November 20, 2013
Mechanisms of heparanase inhibition by the heparan sulfate mimetic PG545 and three structural analoguesEdward Hammond, Paul Handley, Keith Dredge, et al.Frontiers in Oncology|August 9, 2014
The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer TherapeuticsEdward Hammond, Ashwani Khurana, Viji Shridhar, et al.Current Opinion in Investigational Drugs (London, England : 2000)|May 26, 2005
CC-1088 CelgeneKeith DredgeCurrent Opinion in Investigational Drugs (London, England : 2000)|July 10, 2004
AE-941 (AEterna)Keith DredgeBiochemical Pharmacology|May 4, 2020
Sulfated glycolipid PG545 induces endoplasmic reticulum stress and augments autophagic flux by enhancing anticancer chemotherapy efficacy in endometrial cancerRobert Hoffmann, Sayantani Sarkar Bhattacharya, Debarshi Roy, et al.Molecular Cancer Therapeutics|July 19, 2017
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor GrowthArgyris Spyrou, Soumi Kundu, Lulu Haseeb, et al.Seminars in Thrombosis and Hemostasis|July 17, 2007
PI-88 and novel heparan sulfate mimetics inhibit angiogenesisVito Ferro, Keith Dredge, Ligong Liu, et al.Scientific Reports|February 8, 2017
Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian CancerDebarshi Roy, Susmita Mondal, Ashwani Khurana, et al.Pageof 8