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Current Biology : CB|September 17, 2013
Fission yeast does not age under favorable conditions, but does so after stressMiguel Coelho, Aygül Dereli, Anett Haese, et al.
Cell|January 21, 2014
Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding eventsMeredith E Jackrel, Morgan E DeSantis, Bryan A Martinez, et al.
Science Advances|June 24, 2026
Isoform-specific steric zippers drive aberrant assembly and mislocalization of shortened TDP-43Katie E Copley, Megan M Dykstra, Morgan R Miller, et al.
The Journal of Biological Chemistry|December 29, 2019
Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprintingElizabeth A Sweeny, Amber Tariq, Esin Gurpinar, et al.
Nature Structural & Molecular Biology|April 22, 2020
Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysisKyle E Lopez, Alexandrea N Rizo, Eric Tse, et al.
Journal of Molecular Biology|July 22, 2023
Cryo-EM Structure of the Full-length hnRNPA1 Amyloid FibrilKartikay Sharma, Sambhasan Banerjee, Dilan Savran, et al.
Biophysical Journal|April 28, 2019
Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive TranslocasesClarissa L Durie, JiaBei Lin, Nathaniel W Scull, et al.
Molecular Cell|February 19, 2022
Poly(ADP-ribose) drives condensation of FUS via a transient interactionKevin Rhine, Morgan Dasovich, Joseph Yoniles, et al.
Cell Reports|December 13, 2024
Design principles to tailor Hsp104 therapeuticsJiaBei Lin, Peter J Carman, Craig W Gambogi, et al.
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