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Nature Communications|January 8, 2014
Kinetic modelling indicates that fast-translating codons can coordinate cotranslational protein folding by avoiding misfolded intermediatesEdward P O'Brien, Michele Vendruscolo, Christopher M Dobson
Nature Communications|May 31, 2012
Prediction of variable translation rate effects on cotranslational protein foldingEdward P O'Brien, Michele Vendruscolo, Christopher M Dobson
Journal of the American Chemical Society|January 6, 2011
New scenarios of protein folding can occur on the ribosomeEdward P O'Brien, John Christodoulou, Michele Vendruscolo, et al.
Accounts of Chemical Research|May 3, 2014
Understanding the influence of codon translation rates on cotranslational protein foldingEdward P O'Brien, Prajwal Ciryam, Michele Vendruscolo, et al.
Journal of the American Chemical Society|June 12, 2012
Trigger factor slows co-translational folding through kinetic trapping while sterically protecting the nascent chain from aberrant cytosolic interactionsEdward P O'Brien, John Christodoulou, Michele Vendruscolo, et al.
Proceedings of the National Academy of Sciences of the United States of America|December 21, 2012
In vivo translation rates can substantially delay the cotranslational folding of the Escherichia coli cytosolic proteomePrajwal Ciryam, Richard I Morimoto, Michele Vendruscolo, et al.
Scientific Reports|April 20, 2019
Identifying A- and P-site locations on ribosome-protected mRNA fragments using Integer ProgrammingNabeel Ahmed, Pietro Sormanni, Prajwal Ciryam, et al.
Journal of the American Chemical Society|November 11, 2010
Transient tertiary structure formation within the ribosome exit portEdward P O'Brien, Shang-Te Danny Hsu, John Christodoulou, et al.
Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences|January 25, 2005
Towards complete descriptions of the free-energy landscapes of proteinsMichele Vendruscolo, Christopher M Dobson
Current Biology : CB|January 25, 2011
Protein dynamics: Moore's law in molecular biologyMichele Vendruscolo, Christopher M Dobson
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