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Scientific Reports|October 18, 2017
A versatile pretargeting approach for tumour-selective delivery and activation of TNF superfamily membersYuan He, Peter E van Bommel, Douwe F Samplonius, et al.Trends in Molecular Medicine|June 27, 2006
Targeted induction of apoptosis for cancer therapy: current progress and prospectsEdwin Bremer, Go van Dam, Bart Jan Kroesen, et al.Neoplasia (New York, N.Y.)|November 19, 2004
Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cellsEdwin Bremer, Douwe Samplonius, Bart-Jan Kroesen, et al.Blood|December 8, 2005
CD7-restricted activation of Fas-mediated apoptosis: a novel therapeutic approach for acute T-cell leukemiaEdwin Bremer, Bram ten Cate, Douwe F Samplonius, et al.The Journal of Investigative Dermatology|May 26, 2019
Bispecific Antibody Approach for Improved Melanoma-Selective PD-L1 Immune Checkpoint BlockadeIris Koopmans, Mark A J M Hendriks, Robert J van Ginkel, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|September 25, 2008
Potent systemic anticancer activity of adenovirally expressed EGFR-selective TRAIL fusion proteinEdwin Bremer, Gooitzen M van Dam, Marco de Bruyn, et al.Oncoimmunology|September 18, 2018
A novel bispecific antibody for EGFR-directed blockade of the PD-1/PD-L1 immune checkpointIris Koopmans, Djoke Hendriks, Douwe F Samplonius, et al.Oncoimmunology|September 14, 2016
Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis inductionDjoke Hendriks, Yuan He, Iris Koopmans, et al.Journal of Molecular Medicine (Berlin, Germany)|May 28, 2008
Targeted delivery of a designed sTRAIL mutant results in superior apoptotic activity towards EGFR-positive tumor cellsEdwin Bremer, Marco de Bruyn, Douwe F Samplonius, et al.The Journal of Biological Chemistry|January 13, 2005
Simultaneous inhibition of epidermal growth factor receptor (EGFR) signaling and enhanced activation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor-mediated apoptosis induction by an scFv:sTRAIL fusion protein with specificity for human EGFREdwin Bremer, Douwe F Samplonius, Linda van Genne, et al.Pageof 13