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Pharmaceuticals (Basel, Switzerland)|July 2, 2021
Discovery of Selective Inhibitor Leads by Targeting an Allosteric Site in Insulin-Regulated AminopeptidaseIoannis Temponeras, Lykourgos Chiniadis, Athanasios Papakyriakou, et al.
Molecular Immunology|April 22, 2018
Molecular pathways for antigenic peptide generation by ER aminopeptidase 1Anastasia Mpakali, Zachary Maben, Lawrence J Stern, et al.
Journal of Proteome Research|September 15, 2020
Generation of SARS-CoV-2 S1 Spike Glycoprotein Putative Antigenic Epitopes in Vitro by Intracellular AminopeptidasesGeorge Stamatakis, Martina Samiotaki, Anastasia Mpakali, et al.
Frontiers in Immunology|November 4, 2024
Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic propertiesGalateia Georgaki, Anastasia Mpakali, Myrto Trakada, et al.
The Journal of Experimental Medicine|July 18, 2002
Identification of the lateral interaction surfaces of human histocompatibility leukocyte antigen (HLA)-DM with HLA-DR1 by formation of tethered complexes that present enhanced HLA-DM catalysisEfstratios Stratikos, Lidia Mosyak, Dennis M Zaller, et al.
Biochemistry|November 24, 2011
The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processingJames R Birtley, Emmanuel Saridakis, Efstratios Stratikos, et al.
The Journal of Biological Chemistry|October 24, 2021
Allotypic variation in antigen processing controls antigenic peptide generation from SARS-CoV-2 S1 spike glycoproteinGeorge Stamatakis, Martina Samiotaki, Ioannis Temponeras, et al.
Plos One|November 10, 2011
Biophysical analysis of apolipoprotein E3 variants linked with development of type III hyperlipoproteinemiaDimitra Georgiadou, Angeliki Chroni, Alexander Vezeridis, et al.
Protein Science : a Publication of the Protein Society|April 23, 2002
Structural similarity of the covalent complexes formed between the serpin plasminogen activator inhibitor-1 and the arginine-specific proteinases trypsin, LMW u-PA, HMW u-PA, and t-PA: use of site-specific fluorescent probes of local environmentMarija Backovic, Efstratios Stratikos, Daniel A Lawrence, et al.
Nature Communications|September 7, 2021
Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanismZachary Maben, Richa Arya, Dimitris Georgiadis, et al.
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