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Experimental Hematology & Oncology|January 8, 2026
Hypoxia promotes BCMA loss and a suppressive secretome thereby hindering CAR T cell therapy in multiple myelomaChenggong Tu, Arne Van der Vreken, Fien Meeus, et al.
British Journal of Haematology|August 22, 2014
Stimulation of invariant natural killer T cells by α-Galactosylceramide activates the JAK-STAT pathway in endothelial cells and reduces angiogenesis in the 5T33 multiple myeloma modelHaneen Nur, Luigia Rao, Maria Antonia Frassanito, et al.
Cancer Research|May 15, 2007
Inhibition of p38alpha mitogen-activated protein kinase prevents the development of osteolytic bone disease, reduces tumor burden, and increases survival in murine models of multiple myelomaKarin Vanderkerken, Satya Medicherla, Les Coulton, et al.
Blood Cancer Journal|November 10, 2018
Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblastsSylvia Faict, Joséphine Muller, Kim De Veirman, et al.
Cell Death & Disease|February 13, 2021
A distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myelomaPatrick Nylund, Alba Atienza Párraga, Jakob Haglöf, et al.
Blood|June 10, 2010
Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrugJinsong Hu, Damian R Handisides, Els Van Valckenborgh, et al.
Clinical & Experimental Metastasis|November 7, 2006
Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM modelEline Menu, Evy De Leenheer, Hendrik De Raeve, et al.
Frontiers in Cell and Developmental Biology|June 27, 2022
Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment ApproachPhilip Vlummens, Stefaan Verhulst, Kim De Veirman, et al.
Molecular Cancer Therapeutics|July 9, 2013
Synergistic induction of apoptosis in multiple myeloma cells by bortezomib and hypoxia-activated prodrug TH-302, in vivo and in vitroJinsong Hu, Els Van Valckenborgh, Dehui Xu, et al.
Oncotarget|September 9, 2017
Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cellsNathan De Beule, Eline Menu, Mathieu J M Bertrand, et al.
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