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Bioorganic & Medicinal Chemistry Letters|October 14, 2023
Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in miceDaniel H O' Donovan, David Baker, Giovanni Ciotta, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|November 17, 2018
Characterization of Stereoselective Metabolism, Inhibitory Effect on Uric Acid Uptake Transporters, and Pharmacokinetics of Lesinurad AtropisomersChun Yang, Dongmei Zhou, Zancong Shen, et al.The Journal of Infectious Diseases|October 3, 2023
Visualizing Bacterial Infections With Novel Targeted Molecular Imaging ApproachesXueyi Chen, Ferdia Gallagher, Mark A Sellmyer, et al.Nature Communications|October 28, 2020
A protein tertiary structure mimetic modulator of the Hippo signalling pathwayHélène Adihou, Ranganath Gopalakrishnan, Tim Förster, et al.Surgery|June 20, 2016
Performance of magnetic resonance imaging in the evaluation of first-time and reoperative primary hyperparathyroidismWouter P Kluijfhout, Shriya Venkatesh, Toni Beninato, et al.Nucleic Acids Research|August 18, 2009
A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerasesDorjbal Dorjsuren, David M Wilson, William A Beard, et al.Journal of Medicinal Chemistry|August 10, 2018
A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H,2 H,3 H-pyrrolo[3,2- b]pyridin-1-yl)-2-[(2 R,5 R)-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)Christopher N Johnson, Jong Sook Ahn, Ildiko M Buck, et al.Journal of Medicinal Chemistry|April 12, 2019
Structure-Activity and Structure-Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein-Protein InteractionTom D Heightman, James F Callahan, Elisabetta Chiarparin, et al.The Journal of Experimental Medicine|October 5, 2011
XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genesHuseyin Saribasak, Robert W Maul, Zheng Cao, et al.NMR in Biomedicine|July 24, 2015
Real-time measurement of hyperpolarized lactate production and efflux as a biomarker of tumor aggressiveness in an MR compatible 3D cell culture bioreactorRenuka Sriram, Mark Van Criekinge, Ailin Hansen, et al.Pageof 40