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Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|November 10, 2022
Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305Krista Kinneer, Philipp Wortmann, Zachary A Cooper, et al.ACS Chemical Biology|October 19, 2018
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6William McCoull, Tony Cheung, Erica Anderson, et al.Nature|February 9, 2017
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancerGiannicola Genovese, Alessandro Carugo, James Tepper, et al.Journal of Medicinal Chemistry|September 27, 2021
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPsJeffrey W Johannes, Amber Balazs, Derek Barratt, et al.Journal of Medicinal Chemistry|December 10, 2024
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective InhibitorJeffrey W Johannes, Amber Y S Balazs, Derek Barratt, et al.Pageof 5